Underbakke Lab
Architecture and assembly of scaffolded signaling complexes in the Roy J. Carver Dept. of Biochemistry, Biophysics & Molecular Biology.
About Us
Highlighted Publications
Palhano Zanela TM, Zangiabadi M, Zhao Y, Underbakke ES. Molecularly imprinted nanoparticles reveal regulatory scaffolding features in Pyk2 tyrosine kinase. RSC Chem. Biol. (2024) 5, 447-453.
Palhano Zanela TM, Woudenberg A, Romero Bello KG, Underbakke ES. Activation loop phosphorylation tunes conformational dynamics underlying Pyk2 tyrosine kinase activation. Structure 2023 31(4), 447.
Li X, Palhano Zanela TM, Underbakke ES, Zhao Y. Controlling kinase activities by selective inhibition of peptide substrates. J. Am. Chem. Soc. 2021 143(2), 639-643.