Publications

2025

  1. Li, Y., Mei, Y., Schmidt-Danner, M.G., Lv, Y., Peters, R.J., Jia, M. (2025) “Pursuit of a hydroxylation switch uncovers a key residue for various product outcomes in the ent-kaurene synthase from Bradyrhizobium japonicum”, Org. Lett., 27(15):3942-3946. 
    1. Google Scholar: The Pursuit of a Hydroxylation Switch Uncovers a Key Residue for Various Product Outcomes in the ent-Kaurene Synthase from Bradyrhizobium japonicum
  2. Kudjordjie, E.N., Desmedt, W., Kyndt, T., Nicolaisen, M., Peters, R.J., Vestergård, M. (2025) “Diterpenoid phytoalexins shape rice root microbiomes and their association with root parasitic nematodes”, Environ. Microbiol., 27(4):e70084. 
    1. Google Scholar: Diterpenoid phytoalexins shape rice root microbiomes and their associations with root parasitic nematodes
  3. Raslan, A., Peters, R.J. (2025) “Exploring evolutionary use of single residue switches for alternative product outcome in class II diterpene cyclases”, Phytochemistry, 235:114459. 
    1. Google Scholar: Exploring evolutionary use of single residue switches for alternative product outcome in class II diterpene cyclases
  4. Peters, R.J., “Between scents and sterols: Cyclization of labdane-related diterpenes as model systems for enzymatic control of carbocation cascades”, J Biol Chem, vol. 301, art. 108142. 
    1. Google Scholar: Between scents and sterols: Cyclization of labdane-related diterpenes as model systems for enzymatic control of carbocation cascades

2024

  1. Chen, X., Xu, M., Han, J., Schmidt-Dannert, M., Peters, R.J., Chen, F., “Discovery of bifunctional diterpene cyclases/synthases in bacteria supports a bacterial origin for the plant terpene synthase gene family”, Hortic Res, vol. 11, art. uhae221. 
    1. Google Scholar: Discovery of bifunctional diterpene cyclases/synthases in bacteria supports a bacterial origin for the plant terpene synthase gene family 
  2. Feng, Y., Weers, T., Peters, R.J., “Double-barreled defense: Dual ent-miltiradiene synthases in most rice cultivars”, aBIOTECH, vol. 5, pp. 375-380. 
    1. Google Scholar: Double-barreled defense: dual ent-miltiradiene synthases in most rice cultivars
  3. Jin, B., Xu, K., Cui, G., Ma, Y., Yang, J., Chen, N., Zeng, T., Wang, J., Tian, M., Ma, Q., Zhang, H., Peters, R.J., Guo, J., Wu, R., Huang, L., “From functional plasticity of two diterpene synthases (IrKSL2/IrKSL3a) to enzyme evolution”, ACS Catal, vol. 14, pp. 2959-2970. 
    1. Google Scholar: From functional plasticity of two diterpene synthases (IrTPS2/IrKSL3a) to enzyme evolution

2023

  1. Köllner, T.G., Gershenzon, J., Peters, R.J., Zerbe, P., Schmelz, E.A., “The terpene synthase gene family in maize – a clarification of existing community nomenclature”, BMC Genomics, vol. 24, art. 744. 
    1. Google Scholar: The terpene synthase gene family in maize–a clarification of existing community nomenclature
  2. Nagel, R., Alexander, L., Stewart, C.E., Peters, R.J., “Dual Factors Required for Cytochrome-P450 Mediated Ring Contraction in Bacterial Gibberellin Biosynthesis”, Proc Natl Acad Sci USA, vol. 120, art. e2221549120. 
    1. Google Scholar: Dual factors required for cytochrome-P450-mediated hydrocarbon ring contraction in bacterial gibberellin phytohormone biosynthesis
  3. Wang, Z., Peters, R.J., “Dynamic evolution of terpenoid biosynthesis in the Lamiaceae”, Mol Plant, vol. 16, pp. 963-965. 
    1. Google Scholar: Dynamic evolution of terpenoid biosynthesis in the Lamiaceae
  4. Zhao, L., Oyagbenro, R., Xu, M., Peters, R.J., “Oryzalexin S biosynthesis: A cross-stitched disappearing pathway”, aBIOTECH, vol. 4, pp. 1-7. 
    1. Google Scholar: Oryzalexin S biosynthesis: a cross-stitched disappearing pathway
  5. Wang, Z., Nelson, D.R., Zhang, J., Wan, X., Peters, R.J., “Plant (di)terpenoid evolution: From pigments to hormones and beyond”, Nat Prod Rep, vol. 40, pp. 452-469. 
    1. Google Scholar: Plant (di) terpenoid evolution: from pigments to hormones and beyond

2022

  1. Lemke, C., Roach, K., Ortega, T., Tantillo, D.J., Siegel, J.B., Peters, R.J., “Investigation of acid-base catalysis in the halimadienyl diphosphate synthase involved in Mycobacterium tuberculosis virulence”, ACS Bio & Med Chem Au, vol. 2, pp. 490-498. 
    1. Google Scholar: Investigation of Acid–Base Catalysis in Halimadienyl Diphosphate Synthase Involved in Mycobacterium tuberculosis Virulence
  2. Desmedt, W., Kudjordjie, E.N., Chavan, S.N., Zhang, J., Li, R., Yang, B., Mori, M., Peters, R.J., Vanholme, B., Vestergård, M., Kyndt, T., “Rice diterpenoid phytoalexins are involved in defense against parasitic nematodes and shape rhizosphere nematode communities”, New Phytol, vol. 235, pp. 1231-1245. 
    1. Google Scholar: Rice diterpenoid phytoalexins are involved in defence against parasitic nematodes and shape rhizosphere nematode communities
  3. Nett, R.S., Bender, K.S., Peters, R.J., “Production of the plant hormone gibberellin by rhizobia increases host legume nodule size”, ISME J, vol. 16, pp. 1809-1817. 
    1. Google Scholar: Production of the plant hormone gibberellin by rhizobia increases host legume nodule size
  4. Liang, J., Merrill, A.T., Laconsay, C.J., Hou, A., Pu, Q., Dickschat, J.S., Tantillo, D.J., Wang, Q., Peters, R.J., “Deceptive complexity in formation of cleistantha-8,12-diene”, Org Lett, vol. 24, pp. 2646-2649. 
    1. Google Scholar: Deceptive complexity in formation of cleistantha-8, 12-diene
  5. Jia, Q., Brown, R., Köllner, T.G., Fu, J., Chen, X., Wong, K.S.G., Gershenzon, J., Peters, R.J., Chen, F., “Origin and Early Evolution of the Plant Terpene Synthase Family”, Proc Natl Acad Sci USA, vol. 119, art. e2100361119. 
    1. Google Scholar: Origin and early evolution of the plant terpene synthase family
  6. Wang, J., Mao, Y., Ma, Y., Jin, B., Yang, J., Lin, H.X., Zeng, W., Zhao, Y., Gao, W., Peters, R.J., Guo, J., Cui, G., Huang, L., “Diterpene synthases from Leonurus japonicus elucidate epoxy-bridge formation of spiro-labdane diterpenoids”, Plant Physiol, vol. 189, pp. 99-111. 
    1. Google Scholar: Diterpene synthases from Leonurus japonicus elucidate epoxy-bridge formation of spiro-labdane diterpenoids
  7. Wang, Z., Peters, R.J., “Tanshinones: Leading the way into Lamiaceae labdane-related diterpenoid biosynthesis”, Curr Opin Plant Biol, vol. 66, art. e102189. 
    1. Google Scholar: Tanshinones: Leading the way into Lamiaceae labdane-related diterpenoid biosynthesis
  8. Li, R., Zhang, J., Li, Z., Peters, R.J., Yang, B., “Dissecting the labdane-related diterpenoid biosynthetic gene clusters in rice reveals directional cross-cluster phytotoxicity”, New Phytol, vol. 233, pp. 878-889. 
    1. Google Scholar: Dissecting the labdane‐related diterpenoid biosynthetic gene clusters in rice reveals directional cross‐cluster phytotoxicity

2021

  1. Liang, J., An, T., Zhu, J.-X., Chen, S., Zhu, J.-H., Peters, R.J., Yu, R. Zi, J., “Mining of the Catharanthus roseus Genome Leads to Identification of a Biosynthetic Gene Cluster for Fungicidal Sesquiterpenes”, J Nat Prod, vol. 84, pp. 2709-2716. 
    1. Google Scholar: Mining of the Catharanthus roseus Genome Leads to Identification of a Biosynthetic Gene Cluster for Fungicidal Sesquiterpenes
  2. Liang, J., Shen, Q., Wang, L., Liu, J., Fu, J., Zhao, L., Xu, M., Peters, R.J., Wang, Q., “Rice contains a biosynthetic gene cluster associated with production of the casbane-type diterpenoid phytoalexin ent-10-oxodepressin”, New Phytol, vol. 231, pp. 85-93. 
    1. Google Scholar: Rice contains a biosynthetic gene cluster associated with production of the casbane‐type diterpenoid phytoalexin ent‐10‐oxodepressin
  3. Kitaoka, N., Zhang, J., Oyagbenro, R.K., Brown, B., Wu, Y., Yang, B., Li, Z., Peters, R.J., “Interdependent evolution of biosynthetic gene clusters for momilactone production in rice”, Plant Cell, vol. 33, pp. 290-305. 
    1. Google Scholar: Interdependent evolution of biosynthetic gene clusters for momilactone production in rice
  4. Brown, R., Jia, M., Peters, R.J., “A Pair of Threonines Mark ent-Kaurene Synthases for Phytohormone Biosynthesis”, Phytochemistry, vol. 185, art. 112672. 
    1. Google Scholar: A pair of threonines mark ent-kaurene synthases for phytohormone biosynthesis
  5. Zhang, J., Li, R., Xu, M., Hoffmann, R.I., Zhang, Y., Liu, B., Zhang, M., Yang, B., Li, Z., Peters, R.J., “A (Conditional) Role for Labdane-Related Diterpenoid Natural Products in Rice Stomatal Closure”, New Phytol, vol. 230, pp. 698-709. 
    1. Google Scholar: A (conditional) role for labdane‐related diterpenoid natural products in rice stomatal closure
  6. Ma, Y., Cui, G., Chen, T., Ma, X., Wang, R., Jin, B., Yang, J. Kang, L., Tang, J., Lai, C., Wang, Y., Zhao, Y., Shen, Y., Zeng, W. Peters, R.J., Qi, X. Guo, J., Huang, L., “Expansion within the CYP71D subfamily in Salvia miltiorrhiza drove the heterocyclization that characterizes tanshinone biosynthesis”, Nat Commun, vol. 12, art. e685. 
    1. Google Scholar: Expansion within the CYP71D subfamily drives the heterocyclization of tanshinones synthesis in Salvia miltiorrhiza

2020

  1. Lemke, C., Whitham, O., Peters, R.J., “Magnesium-specific ring expansion/ contraction catalysed by the class II diterpene cyclase from pleuromutilin biosynthesis”, Org Biomol Chem, vol. 18, pp. 5586-5588. 
    1. Google Scholar: Magnesium-specific ring expansion/contraction catalysed by the class II diterpene cyclase from pleuromutilin biosynthesis
  2. Liang, J., Wang, L., Liu, J., Shen, Q., Fu, J., Peters, R.J., Wang, Q., “Probing enzymatic structure-function in the di-hydroxylating sesquiterpene synthase ZmEDS”, Biochemistry, vol. 59, pp. 2660-2666. 
    1. Google Scholar: Probing enzymatic structure and function in the dihydroxylating sesquiterpene synthase ZmEDS
  3. Zhang, J., Peters, R.J., “Why are momilactones always associated with biosynthetic gene clusters in plants?”, Proc Natl Acad Sci USA, vol. 117, pp. 13867-13869. 
    1. Google Scholar: Why are momilactones always associated with biosynthetic gene clusters in plants?
  4. Nett, R.S., Nguyen, H., Nagel, R., Marcassa, A., Charles, T.C., Friedberg, I., Peters, R.J., “Unraveling a tangled skein: Evolutionary analysis of the bacterial gibberellin biosynthetic operon”, mSphere, vol. 5, art. e00292-20. 
    1. Google Scholar: Unraveling a tangled skein: evolutionary analysis of the bacterial gibberellin biosynthetic operon
  5. Peters, R.J., “Doing the gene shuffle to close synteny: Dynamic assembly of biosynthetic gene clusters”, New Phyto., vol. 227, pp. 992-994. 
    1. Google Scholar: Doing the gene shuffle to close synteny: dynamic assembly of biosynthetic gene clusters
  6. Pu, X., Tian, Y., Gao, R., Hao, L., Hu, Y., He, C. Xu, M., Peters, R.J., Xu, Z. Song, J., “The honeysuckle genome provides insight into the molecular mechanisms of carotenoid metabolism underlying dynamic flower coloration”, New Phytol, vol. 227, pp. 930-943. 
    1. Google Scholar: The honeysuckle genome provides insight into the molecular mechanism of carotenoid metabolism underlying dynamic flower coloration
  7. Tu, L.-C., Su, P., Zhang, Z.-H., Gao, L.-H., Wang, J.-D., Hu, T.-Y., Zhou, J.-W., Zhang, Y.-F., Zhao, Y.-J., Liu, Y., Xong, Y.-D., Tong, Y.-R., Lu, Y., Yang, J., Xu, C., Jia, M., Peters, R.J., Huang, L., Gao, W., “Genome of Tripterygium wilfordii and identification of cytochrome P450 involved in triptolide biosynthesis”, Nat Commun, vol. 11, art. 971. 
    1. Google Scholar: Genome of Tripterygium wilfordii and identification of cytochrome P450 involved in triptolide biosynthesis
  8. Zhang, J., Zhang, Y., Xing, J., Yu, H., Zhang, R., Tian, X., Duan, L., Zhang, M., Peters, R.J., Li, Z., “Introducing Selective Agrochemical Manipulation of Gibberellin Metabolism into a Cereal Crop”, Nat Plants, vol. 6, pp. 67-72. 
    1. Google Scholar: Introducing selective agrochemical manipulation of gibberellin metabolism into a cereal crop

2019

  1. He, J., Chen, Q., Xin, P., Yuan, J., Ma, Y., Wang, X., Xu, M., Chu, J., Peters, R.J., Wang, G., “CYP72A Enzymes Catalyzing 13-Hydroxylation of Gibberellin are Indispensable for Primary Seed Dormancy in Brassicaceae Plants”, Nat Plants, vol. 5, pp. 1057-1065. 
    1. Google Scholar: CYP72A enzymes catalyse 13-hydrolyzation of gibberellins
  2. Lemke, C., Potter, K.C., Schulte, S., Peters, R.J., “Conserved bases for the initial cyclase in gibberellin phytohormone biosynthesis: from bacteria to plants”, Biochem J, vol. 476, pp. 2607-2621. 
    1. Google Scholar: Conserved bases for the initial cyclase in gibberellin biosynthesis: from bacteria to plants
  3. Jia, M., Zhang, Y., Siegel, J.B., Tantillo, D.J., Peters, R.J., “Switching on a Nontraditional Enzymatic Base – Deprotonation by Serine in the ent-Kaurene Synthase from Bradyrhizobium japonicum”, ACS Catal., vol. 9, pp. 8867-8871. 
    1. Google Scholar: Switching on a Nontraditional Enzymatic Base—Deprotonation by Serine in the ent-Kaurene Synthase from Bradyrhizobium japonicum
  4. Huang, J., Zha, W., An, T., Dong, H., Huang, Y., Wang, D., Yu, R., Duan, L., Zhang, X., Peters, R.J., Dai, Z., Zi, J., “Identification of RoCYP01 (CYP716A155) enables construction of engineered yeast for high-yield production of betulinic acid”, Appl Microbiol Biotechnol, vol. 103, pp. 7029-7039. 
    1. Google Scholar: Identification of RoCYP01 (CYP716A155) enables construction of engineered yeast for high-yield production of betulinic acid
  5. Jia, M., Mishra, S.K., Tufts, S., Jernigan, R.L., Peters, R.J., “Combinatorial biosynthesis and the basis for substrate promiscuity in class I diterpene synthases”, Met Eng, vol. 55, pp. 44-58. 
    1. Google Scholar: Combinatorial biosynthesis and the basis for substrate promiscuity in class I diterpene synthases
  6. Sun, W., Leng, L., Yin, Q., Xu, M., Huang, M., Xu, Z., Zhang, Y., Wang, C., Xiong, C., Chen, S., Jiang, C., Xie, N., Song, C., Peters, R.J., Chen, S., “The genome of the medicinal plant Andrographis paniculata provides insight into biosynthesis of the bioactive diterpenoid neoandrographolide”, Plant J, vol. 97, pp. 841-857. 
    1. Google Scholar: The genome of the medicinal plant Andrographis paniculata provides insight into the biosynthesis of the bioactive diterpenoid neoandrographolide
  7. Nagel, R., Schmidt, A., Peters, R.J., “Isoprenyl diphosphate synthases, the chain length determining step in terpene biosynthesis”, Planta, vol. 249, pp. 9-20. 
    1. Google Scholar: Isoprenyl diphosphate synthases: the chain length determining step in terpene biosynthesis

2018

  1. Nagel, R., Bieber, J., Schmidt-Dannert, M.G., Nett, R.S., Peters, R.J., “A Third Class: Functional Gibberellin Biosynthetic Operon in Beta-Proteobacteria”, Front. Microbiol, vol. 9, art. 2916. 
    1. Google Scholar: A third class: Functional gibberellin biosynthetic operon in beta-proteobacteria
  2. Nagel, R., Thomas, J.A., Adekunle, F.A., Mann, F.M., Peters, R.J., “Arginine in the FARM & SARM: A role in chain-length determination for arginine in the aspartate-rich motifs of isoprenyl diphosphate synthases from Mycobacterium tuberculosis”, Molecules, vol. 23, art. 2546. 
    1. Google Scholar: Arginine in the FARM and SARM: a role in chain-length determination for arginine in the aspartate-rich motifs of isoprenyl diphosphate synthases from Mycobacterium tuberculosis
  3. Nagel, R., Peters, R.J., “Probing the specificity of CYP112 in bacterial gibberellin biosynthesis”, Biochem J, vol. 475, pp. 2167-2177. 
    1. Google Scholar: Probing the specificity of CYP112 in bacterial gibberellin biosynthesis
  4. Schulte, S., Potter, K.P., Lemke, C., Peters, R.J., “Catalytic bases and stereocontrol in Lamiaceae class II diterpene cyclases”, Biochemistry, vol. 57, pp. 3473-3479. 
    1. Google Scholar: Catalytic bases and stereocontrol in Lamiaceae class II diterpene cyclases
  5. Lu, X., Zhang, J., Brown, B., Li, R., Rodríguez-Romero, J., Berasategui, A., Liu, B., Xu, M., Luo, D., Pan, Z., Baerson, S.R., Gershenzon, J., Li, Z., Sesma, A., Yang, B., Peters, R.J., “Inferring roles in defense from metabolic allocation with rice diterpenoids”, Plant Cell, vol. 30, pp. 1119-1131. 
    1. Google Scholar: Inferring roles in defense from metabolic allocation of rice diterpenoids
  6. Liang, J., Liu, J., Jia, M., Brown, R., Zhou, K., Peters, R.J., Wang, Q., “Direct production of dihydroxylated sesquiterpenoids by a maize terpene synthase”, Plant J, vol. 94, pp. 847-856. 
    1. Google Scholar: Direct production of dihydroxylated sesquiterpenoids by a maize terpene synthase
  7. Nagel, R., Peters, R.J., “Diverging Mechanisms: Cytochrome-P450 Catalyzed Demethylation and g-Lactone Formation in Bacterial Gibberellin Biosynthesis”, Angew Chem Int Ed, vol. 57, pp. 6082-6085. 
    1. Google Scholar: Diverging Mechanisms: Cytochrome‐P450‐Catalyzed Demethylation and γ‐Lactone Formation in Bacterial Gibberellin Biosynthesis
  8. Jia, M., O’Brien, T.E., Zhang, Y., Siegel, J.B., Tantillo, D.J., Peters, R.J., “Changing face: A key residue for the addition of water by sclareol synthase”, ACS Catal, vol. 8, pp. 3133-3137. 
    1. Google Scholar: Changing face: a key residue for the addition of water by sclareol synthase
  9. Xu, M., Jia, M., Hong, Y.J., Yin, X., Tantillo, D.J., Proteau, P.J., Peters, R.J., “Premutilin synthase: Ring rearrangement by a class II diterpene cyclase”, Org Lett, vol. 20, pp. 1200-1202. 
    1. Google Scholar: Premutilin synthase: ring rearrangement by a class II diterpene cyclase
  10. Su, P., Guan, H., Zhao, Y., Tong, Y., Xu, M., Zhang, Y., Hu, T., Yang, J., Cheng, Q., Gao, L., Liu, Y., Zhou, J., Peters, R.J., Huang, L., Gao, W., “Identification and functional characterization of diterpene synthases for triptolide biosynthesis from Tripterygium wilfordii”, Plant J, vol. 93, pp. 50-63. 
    1. Google Scholar: Identification and functional characterization of diterpene synthases for triptolide biosynthesis from Tripterygium wilfordii

2017

  1. Nagel, R., Peters, R.J., “18O2 labeling studies illuminate the oxidation of ent-kaurene in bacterial gibberellin biosynthesis”, Org Biomol Chem, vol. 15, pp. 7566-7571. 
    1. Google Scholar: 18 O 2 labeling experiments illuminate the oxidation of ent-kaurene in bacterial gibberellin biosynthesis
  2. Inabuy, F.X., Fischedick, J.T., Lange, I., Hartmann, M., Srividya, N., Parrish, A.N., Xu, M., Peters, R.J., Lange, B.M., “Biosynthesis of diterpenoids in Tripterygium adventitious root cultures”, Plant Physiol, vol. 175, pp. 92-103. 
    1. Google Scholar: Biosynthesis of Diterpenoids in Tripterygium Adventitious Root Cultures
  3. Nagel, R., Peters, R.J., “Investigating the phylogenetic range of gibberellin biosynthesis in bacteria”, Mol Plant-Microbe Interact, vol. 30, pp. 343-349. 
    1. Google Scholar: Investigating the phylogenetic range of gibberellin biosynthesis in bacteria
  4. Nett, R.S., Contreras, T., Peters, R.J., “Characterization of CYP115 as a gibberellin 3-oxidase indicates that certain rhizobia can produce bioactive gibberellin A4”, ACS Chem Biol, vol. 12, pp. 912-917. 
    1. Google Scholar: Characterization of CYP115 As a Gibberellin 3-Oxidase Indicates That Certain Rhizobia Can Produce Bioactive Gibberellin A4
  5. Jia, M., Peters, R.J., “cis or trans with class II diterpene cyclases”, Org Biomol Chem, vol. 15, pp. 3158-3160. 
    1. Google Scholar: Cis or Trans with class II diterpene cyclases
  6. Nagel, R., Turrini, P., Nett, R.S., Leach, J.E., Verdier, V., Van Sluys, M.-A., Peters, R.J., “An operon for production of bioactive gibberellin A4 phytohormone with wide distribution in the bacterial rice leaf streak pathogen Xanthomonas oryzae pv. oryzicola”, New Phytol, vol. 214, pp. 1260-1266. 
    1. Google Scholar: An operon for production of bioactive gibberellin A4 phytohormone with wide distribution in the bacterial rice leaf streak pathogen Xanthomonas oryzae pv. oryzicola
  7. Jia, M., Zhou, K., Tufts, S., Schulte, S., Peters, R.J., “A pair of residues that interactively affect diterpene synthase product outcome”, ACS Chem Biol, vol. 12, pp. 862-867. 
    1. Google Scholar: A pair of residues that interactively affect diterpene synthase product outcome
  8. Xu, M., Hillwig, M.L., Tiernan, M.S., Peters, R.J., “Probing labdane-related diterpenoid biosynthesis in the fungal genus Aspergillus”, J Nat Prod, vol. 80, pp. 328-333. 
    1. Google Scholar: Probing Labdane-Related Diterpenoid Biosynthesis in the Fungal Genus Aspergillus
  9. Nett, R.S., Montanares, M., Marcassa, A., Lu, X., Nagel, R., Charles, T.C., Hedden, P., Rojas, M.C., Peters, R.J., “Elucidation of gibberellin biosynthesis in bacteria reveals convergent evolution”, Nat Chem Biol, vol. 13, pp. 69-74. 
    1. Google Scholar: Elucidation of gibberellin biosynthesis in bacteria reveals convergent evolution

2016

  1. Nett, R.S., Dickschat, J.S., Peters, R.J., “Labeling studies clarify the committed step in bacterial gibberellin biosynthesis”, Org Lett, vol. 18, pp. 5974-5977. 
    1. Google Scholar: Labeling studies clarify the committed step in bacterial gibberellin biosynthesis
  2. Jia, M., Peters, R.J., “Extending a single residue switch for abbreviating catalysis in plant ent-kaurene synthases”, Front Plant Sci, vol. 7, art. 1765. 
    1. Google Scholar: Extending a Single Residue Switch for Abbreviating Catalysis in Plant ent-Kaurene Synthases
  3. Wang, Q., Jia, M., Huh, J.-H., Peters, R.J., Tholl, D., “Identification of a Dolabellane Type Diterpene Synthase and other Root-Expressed Diterpene Synthases in Arabidopsis”, Front Plant Sci, vol. 7, art. 1761. 
    1. Google Scholar: Identification of a Dolabellane Type Diterpene Synthase and other Root-Expressed Diterpene Synthases in Arabidopsis
  4. Kumar, S., Kempinski, C., Zhuang, X., Norris, A., Mafu, S., Zi, J., Bell, S., Nybo, S., Kinison, S., Jiang, Z., Goklany, S., Linscott, K., Chen, X., Jia, Q., Brown, S., Bowman, J. Babbitt, P. Peters, R.J., Chen, F., Chappell, J., “Molecular Diversity of Terpene Synthases in the Liverwort Marchantia polymorpha”, Plant Cell, vol. 28, pp. 2632-2650. 
    1. Google Scholar: Molecular Diversity of Terpene Synthases in the Liverwort Marchantia polymorpha
  5. Kitaoka, N., Wu, Y., Wang, Q., Zi, J., Peters, R.J., “Investigating inducible short-chain alcohol dehydrogenases/reductases clarifies rice oryzalexin biosynthesis”, Plant J, vol. 88, pp. 271-279. 
    1. Google Scholar: Investigating inducible short‐chain alcohol dehydrogenases/reductases clarifies rice oryzalexin biosynthesis
  6. Xu, H., Song, J., Luo, H., Li, Q., Zhu, Y., Xu, J., Li, Y., Song, C., Wang, B., Sun, W., Shen, G., Zhang, X., Qian, J., Zhang, Y., Ji, A., Xu, Z., Luo, X., He, L., Li, C., Sun, C., Yan, H., Cui, G., Li, X., Wei, J., Li, X., Liu, J., Wang, Y., Hayward, A., Nelson, D., Ning, Z., Peters, R.J., Qi, X., Chen, S., “Analysis of the genome sequence of the medicinal plant Salvia miltiorrhiza”, Mol Plant, vol. 9, pp. 949-952. 
    1. Google Scholar: Analysis of the genome sequence of the medicinal plant Salvia miltiorrhiza
  7. Jia, M., Potter, K.C., Peters, R.J., “Extreme promiscuity of a bacterial and a plant diterpene synthase enables combinatorial biosynthesis”, Met Eng, vol. 37, pp. 24-34. 
    1. Google Scholar: Extreme promiscuity of a bacterial and a plant diterpene synthase enables combinatorial biosynthesis
  8. Potter, K.C., Jia, M., Young, Y.J., Tantillo, D.J., Peters, R.J., “Product rearrangement from altering a single residue in the rice syn-copalyl diphosphate synthase”, Org Lett, vol. 18, pp. 1060-1063. 
    1. Google Scholar: Product Rearrangement from Altering a Single Residue in the Rice syn-Copalyl Diphosphate Synthase
  9. K. C. Potter, Zi, J., Hong, Y. J., Schulte, S., Malchow, B., Tantillo, D. J., and Peters, R. J., “Blocking Deprotonation with Retention of Aromaticity in a Plant ent-Copalyl Diphosphate Synthase Leads to Product Rearrangement”, Angew Chem Int Ed Eng, vol. 55, no. 2, pp. 634-638, 2016.
    1. Google Scholar: Blocking Deprotonation with Retention of Aromaticity in a Plant ent‐Copalyl Diphosphate Synthase Leads to Product Rearrangement
  10. H. Mao, Liu, J., Ren, F., Peters, R. J., and Wang, Q., “Characterization of CYP71Z18 indicates a role in maize zealexin biosynthesis”, Phytochemistry, vol. 121, pp. 4-10, 2016.
    1. Google Scholar: Characterization of CYP71Z18 indicates a role in maize zealexin biosynthesis.
  11. J. Guo, Ma, X., Cai, Y., Ma, Y., Zhan, Z., Zhou, Y. J., Liu, W., Guan, M., Yang, J., Cui, G., Kang, L., Yang, L., Shen, Y., Tang, J., Lin, H., Ma, X., Jin, B., Liu, Z., Peters, R. J., Zhao, Z. K., and Huang, L., “Cytochrome P450 promiscuity leads to a bifurcating biosynthetic pathway for tanshinones”, New Phytol, vol. 210, pp. 525-534, 2016.
    1. Google Scholar: Cytochrome P450 promiscuity leads to a bifurcating biosynthetic pathway for tanshinones
  12. S. Mafu, Jia, M., Zi, J., Xu, M., Morrone, D., Wu, Y., and Peters, R. J., “Probing the promiscuity of ent-kaurene oxidase via combinatorial biosynthesis”, Proc Natl Acad Sci U S A, vol. 113, pp. 2526-2531, 2016. 
    1. Google Scholar: Probing the promiscuity of ent-kaurene oxidases via combinatorial biosynthesis
  13. J. Fu, Ren, F., Lu, X., Mao, H., Xu, M., Degenhardt, J., Peters, R. J., and Wang, Q., “A tandem array of ent-kaurene synthases in maize with roles in gibberellin and more specialized metabolism”, Plant Physiol, vol. 170, pp. 742-751, 2016.
    1. Google Scholar: A Tandem Array of ent-Kaurene Synthases in Maize with Roles in Gibberellin and More Specialized Metabolism

2015

  1. N. Kitaoka, Lu, X., Yang, B., and Peters, R. J., “The application of synthetic biology to elucidation of plant mono-, sesqui-, and diterpenoid metabolism”, Mol Plant, vol. 8, pp. 6-16, 2015. 
    1. Google Scholar: The application of synthetic biology to elucidation of plant mono-, sesqui-, and diterpenoid metabolism
  2. Y. Matsuba, Zi, J., Jones, A. D., Peters, R. J., and Pichersky, E., “Biosynthesis of the Diterpenoid Lycosantalonol via Nerylneryl Diphosphate in Solanum lycopersicum”, PLoS One, vol. 10, p. e0119302, 2015.
    1. Google Scholar: Biosynthesis of the diterpenoid lycosantalonol via nerylneryl diphosphate in Solanum lycopersicum
  3. S. Mafu, Potter, K. C., Hillwig, M. L., Schulte, S., Criswell, J., and Peters, R. J., “Efficient heterocyclisation by (di)terpene synthases”, Chem Commun (Camb), vol. 51, no. 70, pp. 13485-7, 2015. 
    1. Google Scholar: Efficient heterocyclisation by (di) terpene synthases
  4. X. Lu, Hershey, D. M., Wang, L., Bogdanove, A. J., and Peters, R. J., “An ent-kaurene-derived diterpenoid virulence factor from Xanthomonas oryzae pv. oryzicola”, New Phytol, vol. 206, pp. 295-302, 2015.
    1. Google Scholar: An ent‐kaurene‐derived diterpenoid virulence factor from Xanthomonas oryzae pv. oryzicola
  5. Z. Xu, Peters, R. J., Weirather, J., Luo, H., Liao, B., Zhang, X., Zhu, Y., Ji, A., Zhang, B., Hu, S., Au, K. F., Song, J., and Chen, S., “Full-length transcriptome sequences and splice variants obtained by a combination of sequencing platforms applied to different root tissues of Salvia miltiorrhiza and tanshinone biosynthesis”, Plant J, vol. 82, pp. 951-61, 2015. 
    1. Google Scholar: Full-length transcriptome sequences and splice variants obtained by a combination of sequencing platforms applied to different root tissues of Salvia miltiorrhiza and tanshinone biosynthesis
  6. G. Cui, Duan, L., Jin, B., Qian, J., Xue, Z., Shen, G., Snyder, J. H., Song, J., Chen, S., Huang, L., Peters, R. J., and Qi, X., “Functional divergence of diterpene synthases in the medicinal plant Salvia miltiorrhiza”, Plant Physiol, vol. 169, pp. 1607-1618, 2015. 
    1. Google Scholar: Functional Divergence of Diterpene Syntheses in the Medicinal Plant Salvia miltiorrhiza
  7. A. M. Boutanaev, Moses, T., Zi, J., Nelson, D. R., Mugford, S. T., Peters, R. J., and Osbourn, A., “Investigation of terpene diversification across multiple sequenced plant genomes”, Proc Natl Acad Sci U S A, vol. 112, pp. E81-8, 2015. 
    1. Google Scholar: Investigation of terpene diversification across multiple sequenced plant genomes
  8. A. T. Klein, Yagnik, G. B., Hohenstein, J. D., Ji, Z., Zi, J., Reichert, M. D., MacIntosh, G. C., Yang, B., Peters, R. J., Vela, J., and Lee, Y. J., “Investigation of the Chemical Interface in the Soybean-Aphid and Rice-Bacteria Interactions Using MALDI-Mass Spectrometry Imaging”, Anal Chem, vol. 87, no. 10, pp. 5294-5301, 2015. 
    1. Google Scholar: Investigation of the chemical interface in the soybean–aphid and rice–bacteria interactions using MALDI-mass spectrometry imaging
  9. N. Kitaoka, Wu, Y., Xu, M., and Peters, R. J., “Optimization of recombinant expression enables discovery of novel cytochrome P450 activity in rice diterpenoid biosynthesis”, Appl Microbiol Biotechnol, vol. 99, no. 18, 2015. 
    1. Google Scholar: Optimization of recombinant expression enables discovery of novel cytochrome P450 activity in rice diterpenoid biosynthesis

2014

  1. M. Köksal, Potter, K., Peters, R. J., and Christianson, D. W., “1.55 Å-resolution structure of ent-copalyl diphosphate synthase and exploration of general acid function by site-directed mutagenesis”, Biochimica et Biophysica Acta (BBA), vol. 1840, no. 1, pp. 184-190, 2014. 
    1. Google Scholar: 1.55 Å-resolution structure of ent-copalyl diphosphate synthase and exploration of general acid function by site-directed mutagenesis
  2. A. J. Jackson, Hershey, D. M., Chesnut, T., Xu, M., and Peters, R. J., “Biochemical characterization of the castor bean ent-kaurene synthase(-like) family supports quantum chemical view of diterpene cyclization”, Phytochemistry, vol. 103, pp. 13-21, 2014.
    1. Google Scholar: Biochemical characterization of the castor bean ent-kaurene synthase(-like) family supports quantum chemical view of diterpene cyclization
  3. E. A. Schmelz, Huffaker, A., Sims, J. W., Christensen, S. A., Lu, X., Okada, K., and Peters, R. J., “Biosynthesis, elicitation and roles of monocot terpenoid phytoalexins”, The Plant Journal, vol. 79, no. 4, pp. 659-678, 2014.
    1. Google Scholar: Biosynthesis, elicitation and roles of monocot terpenoid phytoalexins
  4. J. Zi, Matsuba, Y., Hong, Y. J., Jackson, A. J., Tantillo, D. J., Pichersky, E., and Peters, R. J., “Biosynthesis of lycosantalonol, a cis-prenyl derived diterpenoid”, J Am Chem Soc, vol. 136, pp. 16951-3, 2014.
    1. Google Scholar: Biosynthesis of Lycosantalonol, a cis-Prenyl Derived Diterpenoid
  5. M. Xu, Hillwig, M. L., Lane, A. L., Tiernan, M. S., Moore, B. S., and Peters, R. J., “Characterization of an Orphan Diterpenoid Biosynthetic Operon from Salinispora arenicola”, Journal of natural products, vol. 77, no. 9, pp. 2144-2147, 2014.
    1. Google Scholar: Characterization of an Orphan Diterpenoid Biosynthetic Operon from Salinispora arenicola
  6. W. Gao, Sun, H. - X., Xiao, H., Cui, G., Hillwig, M. L., Jackson, A., Wang, X., Shen, Y., Zhao, N., and Zhang, L., “Combining metabolomics and transcriptomics to characterize tanshinone biosynthesis in Salvia miltiorrhiza”, BMC genomics, vol. 15, no. 1, p. 73, 2014.
    1. Google Scholar: Combining metabolomics and transcriptomics to characterize tanshinone biosynthesis in Salvia miltiorrhiza.
  7. D. M. Hershey, Lu, X., Zi, J., and Peters, R. J., “Functional conservation of the capacity for ent-kaurene biosynthesis and an associated operon in certain rhizobia”, Journal of bacteriology, vol. 196, no. 1, pp. 100-106, 2014. 
    1. Google Scholar: Functional Conservation of the Capacity for ent-Kaurene Biosynthesis and an Associated Operon in Certain Rhizobia
  8. K. Potter, Criswell, J., Zi, J., Stubbs, A., and Peters, R. J., “Novel Product Chemistry from Mechanistic Analysis of ent‐Copalyl Diphosphate Synthases from Plant Hormone Biosynthesis”, Angewandte Chemie International Edition, vol. 53, pp. 7198-7202, 2014. 
    1. Google Scholar: Novel Product Chemistry from Mechanistic Analysis of ent‐Copalyl Diphosphate Synthases from Plant Hormone Biosynthesis
  9. J. Zi, Mafu, S., and Peters, R. J., “To Gibberellins and Beyond! Surveying the Evolution of (Di)Terpenoid Metabolism”, Annual review of plant biology, vol. 65, pp. 259-286, 2014. 
    1. Google Scholar: To gibberellins and beyond! Surveying the evolution of (di) terpenoid metabolism

2013

  1. J. Zi and Peters, R. J., “Characterization of CYP76AH4 clarifies phenolic diterpenoid biosynthesis in the Lamiaceae”, Organic & biomolecular chemistry, vol. 11, no. 44, pp. 7650-7652, 2013.
    1. Google Scholar: Characterization of CYP76AH4 clarifies phenolic diterpenoid biosynthesis in the Lamiaceae
  2. J. Guo, Zhou, Y. J., Hillwig, M. L., Shen, Y., Yang, L., Wang, Y., Zhang, X., Liu, W., Peters, R. J., and Chen, X., “CYP76AH1 catalyzes turnover of miltiradiene in tanshinones biosynthesis and enables heterologous production of ferruginol in yeasts”, Proceedings of the National Academy of Sciences, vol. 110, no. 29, pp. 12108-12113, 2013.
    1. Google Scholar: CYP76AH1 catalyzes turnover of miltiradiene in tanshinones biosynthesis and enables heterologous production of ferruginol in yeasts
  3. R. J. Peters, “Gibberellin phytohormone metabolism”, in Isoprenoid Synthesis in Plants and Microorganisms, Springer New York, 2013, pp. 233-249. 
    1. Google Scholar: Gibberellin phytohormone metabolism
  4. W. Yisheng, Qiang, W., L Matthew, H., and J Reuben, P., “Picking sides: distinct roles for CYP76M6 and CYP76M8 in rice oryzalexin biosynthesis”, Biochemical Journal, vol. 454, no. 2, pp. 209-216, 2013. 
    1. Google Scholar: Picking sides: distinct roles for CYP76M6 and CYP76M8 in rice oryzalexin biosynthesis
  5. H. Kato-Noguchi and Peters, R. J., “The role of momilactones in rice allelopathy”, Journal of chemical ecology, vol. 39, no. 2, pp. 175-185, 2013. 
    1. Google Scholar: The role of momilactones in rice allelopathy

2012

  1. Q. Wang, Hillwig, M. L., Okada, K., Yamazaki, K., Wu, Y., Swaminathan, S., Yamane, H., and Peters, R. J., “Characterization of CYP76M5–8 indicates metabolic plasticity within a plant biosynthetic gene cluster”, Journal of Biological Chemistry, vol. 287, no. 9, pp. 6159-6168, 2012.
    1. Google Scholar: Characterization of CYP76M5–8 indicates metabolic plasticity within a plant biosynthetic gene cluster
  2. Q. Wang, Hillwig, M. L., Wu, Y., and Peters, R. J., “CYP701A8: a rice ent-kaurene oxidase paralog diverted to more specialized diterpenoid metabolism”, Plant physiology, vol. 158, no. 3, pp. 1418-1425, 2012.
    1. Google Scholar: CYP701A8: A Rice ent-Kaurene Oxidase Paralog Diverted to More Specialized Diterpenoid Metabolism
  3. L. Zu, Xu, M., Lodewyk, M. W., Cane, D. E., Peters, R. J., and Tantillo, D. J., “Effect of isotopically sensitive branching on product distribution for pentalenene synthase: support for a mechanism predicted by quantum chemistry”, Journal of the American Chemical Society, vol. 134, no. 28, pp. 11369-11371, 2012. 
    1. Google Scholar: Effect of isotopically sensitive branching on product distribution for pentalenene synthase: support for a mechanism predicted by quantum chemistry
  4. F. M. Mann, Xu, M., Davenport, E. K., and Peters, R. J., “Functional characterization and evolution of the isotuberculosinol operon in Mycobacterium tuberculosis and related Mycobacteria”, Frontiers in microbiology, vol. 3, 2012. 
    1. Google Scholar: Functional characterization and evolution of the isotuberculosinol operon in Mycobacterium tuberculosis and related Mycobacteria
  5. Y. Wu, Zhou, K., Toyomasu, T., Sugawara, C., Oku, M., Abe, S., Usui, M., Mitsuhashi, W., Chono, M., and Chandler, P. M., “Functional characterization of wheat copalyl diphosphate synthases sheds light on the early evolution of labdane-related diterpenoid metabolism in the cereals”, Phytochemistry, vol. 84, pp. 40-46, 2012. 
    1. Google Scholar: Functional characterization of wheat copalyl diphosphate synthases sheds light on the early evolution of labdane-related diterpenoid metabolism in the cereals
  6. K. Zhou, Xu, M., Tiernan, M., Xie, Q., Toyomasu, T., Sugawara, C., Oku, M., Usui, M., Mitsuhashi, W., and Chono, M., “Functional characterization of wheat ent-kaurene(-like) synthases indicates continuing evolution of labdane-related diterpenoid metabolism in the cereals”, Phytochemistry, vol. 84, pp. 47-55, 2012. 
    1. Google Scholar: Functional characterization of wheat ent-kaurene(-like) synthases indicates continuing evolution of labdane-related diterpenoid metabolism in the cereals
  7. M. Xu, Galhano, R., Wiemann, P., Bueno, E., Tiernan, M., Wu, W., Chung, I. ‐M., Gershenzon, J., Tudzynski, B., and Sesma, A., “Genetic evidence for natural product‐mediated plant–plant allelopathy in rice (Oryza sativa)”, New Phytologist, vol. 193, no. 3, pp. 570-575, 2012. 
    1. Google Scholar: Genetic evidence for natural product‐mediated plant–plant allelopathy in rice (Oryza sativa)
  8. K. Zhou, Gao, Y., Hoy, J. A., Mann, F. M., Honzatko, R. B., and Peters, R. J., “Insights into diterpene cyclization from structure of bifunctional abietadiene synthase from Abies grandis”, Journal of Biological Chemistry, vol. 287, no. 9, pp. 6840-6850, 2012. 
    1. Google Scholar: Insights into diterpene cyclization from structure of bifunctional abietadiene synthase from Abies grandis
  9. F. M. Mann and Peters, R. J., “Isotuberculosinol: the unusual case of an immunomodulatory diterpenoid from Mycobacterium tuberculosis”, Med. Chem. Commun., vol. 3, no. 8, pp. 899-904, 2012. 
    1. Google Scholar: Isotuberculosinol: the unusual case of an immunomodulatory diterpenoid from Mycobacterium tuberculosis
  10. J. Criswell, Potter, K., Shephard, F., Beale, M. H., and Peters, R. J., “A single residue change leads to a hydroxylated product from the class II diterpene cyclization catalyzed by abietadiene synthase”, Organic letters, vol. 14, no. 23, pp. 5828-5831, 2012.
    1. Google Scholar: A single residue change leads to a hydroxylated product from the class II diterpene cyclization catalyzed by abietadiene synthase
  11. Y. Gao, Honzatko, R. B., and Peters, R. J., “Terpenoid synthase structures: a so far incomplete view of complex catalysis”, Natural product reports, vol. 29, no. 10, pp. 1153-1175, 2012. 
    1. Google Scholar: Terpenoid synthase structures: a so far incomplete view of complex catalysis

2011

  1. Q. Wang, Hillwig, M. L., and Peters, R. J., “CYP99A3: functional identification of a diterpene oxidase from the momilactone biosynthetic gene cluster in rice”, The Plant Journal, vol. 65, no. 1, pp. 87-95, 2011.
    1. Google Scholar: CYP99A3: functional identification of a diterpene oxidase from the momilactone biosynthetic gene cluster in rice
  2. M. L. Hillwig, Mann, F. M., and Peters, R. J., “Diterpenoid biopolymers: new directions for renewable materials engineering”, Biopolymers, vol. 95, no. 2, pp. 71-76, 2011. 
    1. Google Scholar: Diterpenoid biopolymers: new directions for renewable materials engineering
  3. M. L. Hillwig, Xu, M., Toyomasu, T., Tiernan, M. S., Wei, G., Cui, G., Huang, L., and Peters, R. J., “Domain loss has independently occurred multiple times in plant terpene synthase evolution”, The Plant Journal, vol. 68, no. 6, pp. 1051-1060, 2011. 
    1. Google Scholar: Domain loss has independently occurred multiple times in plant terpene synthase evolution
  4. K. Zhou and Peters, R. J., “Electrostatic effects on (di)terpene synthase product outcome”, Chemical Communications, vol. 47, no. 14, pp. 4074-4080, 2011. 
    1. Google Scholar: Electrostatic effects on (di) terpene synthase product outcome
  5. D. Morrone, Hillwig, M., Mead, M., Lowry, L., Fulton, D., and Peters, R., “Evident and latent plasticity across the rice diterpene synthase family with potential implications for the evolution of diterpenoid metabolism in the cereals”, Biochem. J, vol. 435, pp. 589-595, 2011. 
    1. Google Scholar: Evident and latent plasticity across the rice diterpene synthase family with potential implications for the evolution of diterpenoid metabolism in the cereals
  6. F. M. Mann, VanderVen, B. C., and Peters, R. J., “Magnesium depletion triggers production of an immune modulating diterpenoid in Mycobacterium tuberculosis”, Molecular microbiology, vol. 79, no. 6, pp. 1594-1601, 2011. 
    1. Google Scholar: Magnesium depletion triggers production of an immune modulating diterpenoid in Mycobacterium tuberculosis
  7. S. Mafu, Hillwig, M. L., and Peters, R. J., “A Novel Labda‐7,13E‐dien‐15‐ol‐Producing Bifunctional Diterpene Synthase from Selaginella moellendorffii”, ChemBioChem, vol. 12, no. 13, pp. 1984-1987, 2011.
    1. Google Scholar: A Novel Labda‐7,13E‐dien‐15‐ol‐Producing Bifunctional Diterpene Synthase from Selaginella moellendorffii
  8. Y. Wu, Hillwig, M. L., Wang, Q., and Peters, R. J., “Parsing a multifunctional biosynthetic gene cluster from rice: Biochemical characterization of CYP71Z6 & 7”, FEBS letters, vol. 585, no. 21, pp. 3446-3451, 2011. 
    1. Google Scholar: Parsing a multifunctional biosynthetic gene cluster from rice: Biochemical characterization of CYP71Z6 & 7
  9. F. M. Mann, Thomas, J. A., and Peters, R. J., “Rv0989c encodes a novel (E)-geranyl diphosphate synthase facilitating decaprenyl diphosphate biosynthesis in Mycobacterium tuberculosis”, FEBS letters, vol. 585, no. 3, pp. 549-554, 2011. 
    1. Google Scholar: Rv0989c encodes a novel (E)-geranyl diphosphate synthase facilitating decaprenyl diphosphate biosynthesis in Mycobacterium tuberculosis
  10. M. Köksal, Hu, H., Coates, R. M., Peters, R. J., and Christianson, D. W., “Structure and mechanism of the diterpene cyclase ent-copalyl diphosphate synthase”, Nature chemical biology, vol. 7, no. 7, pp. 431-433, 2011. 
    1. Google Scholar: Structure and mechanism of the diterpene cyclase ent-copalyl diphosphate synthase

2010

  1. D. Morrone, Chen, X., Coates, R., and Peters, R., “Characterization of the kaurene oxidase CYP701A3, a multifunctional cytochrome P450 from gibberellin biosynthesis”, Biochem. J, vol. 431, pp. 337-344, 2010.
    1. Google Scholar: Characterization of the kaurene oxidase CYP701A3, a multifunctional cytochrome P450 from gibberellin biosynthesis
  2. R. Cao, Zhang, Y., Mann, F. M., Huang, C., Mukkamala, D., Hudock, M. P., Mead, M. E., Prisic, S., Wang, K., and Lin, F. ‐Y., “Diterpene cyclases and the nature of the isoprene fold”, Proteins: Structure, Function, and Bioinformatics, vol. 78, no. 11, pp. 2417-2432, 2010. 
    1. Google Scholar: Diterpene cyclases and the nature of the isoprene fold
  3. D. Morrone, Lowry, L., Determan, M. K., Hershey, D. M., Xu, M., and Peters, R. J., “Increasing diterpene yield with a modular metabolic engineering system in E. coli: comparison of MEV and MEP isoprenoid precursor pathway engineering”, Applied microbiology and biotechnology, vol. 85, no. 6, pp. 1893-1906, 2010. 
    1. Google Scholar: Increasing diterpene yield with a modular metabolic engineering system in E. coli: comparison of MEV and MEP isoprenoid precursor pathway engineering
  4. F. M. Mann, Prisic, S., Davenport, E. K., Determan, M. K., Coates, R. M., and Peters, R. J., “A single residue switch for Mg2+-dependent inhibition characterizes plant class II diterpene cyclases from primary and secondary metabolism”, Journal of Biological Chemistry, vol. 285, no. 27, pp. 20558-20563, 2010.
    1. Google Scholar: A single residue switch for Mg2+-dependent inhibition characterizes plant class II diterpene cyclases from primary and secondary metabolism
  5. N. Maugel, Mann, F. M., Hillwig, M. L., Peters, R. J., and Snider, B. B., “Synthesis of (±)-Nosyberkol (Isotuberculosinol, Revised Structure of Edaxadiene) and (±)-Tuberculosinol”, Organic letters, vol. 12, no. 11, pp. 2626-2629, 2010. 
    1. Google Scholar: Synthesis of (±)-nosyberkol (isotuberculosinol, revised structure of edaxadiene) and (±)-tuberculosinol
  6. R. J. Peters, “Two rings in them all: the labdane-related diterpenoids”, Natural product reports, vol. 27, no. 11, pp. 1521-1530, 2010. 
    1. Google Scholar: Two rings in them all: the labdane-related diterpenoids

2009

  1. F. M. Mann, Prisic, S., Hu, H., Xu, M., Coates, R. M., and Peters, R. J., “Characterization and Inhibition of a Class II Diterpene Cyclase from Mycobacterium tuberculosis IMPLICATIONS FOR TUBERCULOSIS”, Journal of Biological Chemistry, vol. 284, no. 35, pp. 23574-23579, 2009
    1. Google Scholar: Characterization and inhibition of a class II diterpene cyclase from Mycobacterium tuberculosis: implications for tuberculosis
  2. S. Swaminathan, Morrone, D., Wang, Q., D Fulton, B., and Peters, R. J., “CYP76M7 is an ent-cassadiene C11α-hydroxylase defining a second multifunctional diterpenoid biosynthetic gene cluster in rice”, The Plant Cell Online, vol. 21, no. 10, pp. 3315-3325, 2009.
    1. Google Scholar: CYP76M7 Is an ent-Cassadiene C11α-Hydroxylase Defining a Second Multifunctional Diterpenoid Biosynthetic Gene Cluster in Rice
  3. F. M. Mann, Xu, M., Chen, X., D Fulton, B., Russell, D. G., and Peters, R. J., “Edaxadiene: a new bioactive diterpene from Mycobacterium tuberculosis”, Journal of the American Chemical Society, vol. 131, no. 48, pp. 17526-17527, 2009. 
    1. Google Scholar: Edaxadiene: A New Bioactive Diterpene from Mycobacterium tuberculosis
  4. W. Gao, Hillwig, M. L., Huang, L., Cui, G., Wang, X., Kong, J., Yang, B., and Peters, R. J., “A functional genomics approach to tanshinone biosynthesis provides stereochemical insights”, Organic letters, vol. 11, no. 22, pp. 5170-5173, 2009.
    1. Google Scholar: A functional genomics approach to tanshinone biosynthesis provides stereochemical insights
  5. D. Morrone, Chambers, J., Lowry, L., Kim, G., Anterola, A., Bender, K., and Peters, R. J., “Gibberellin biosynthesis in bacteria: Separate ent-copalyl diphosphate and ent-kaurene synthases in Bradyrhizobium japonicum”, FEBS letters, vol. 583, no. 2, pp. 475-480, 2009. 
    1. Google Scholar: Gibberellin biosynthesis in bacteria: Separate ent-copalyl diphosphate and ent-kaurene synthases in Bradyrhizobium japonicum
  6. K. Zhou and Peters, R. J., “Investigating the conservation pattern of a putative second terpene synthase divalent metal binding motif in plants”, Phytochemistry, vol. 70, no. 3, pp. 366-369, 2009. 
    1. Google Scholar: Investigating the conservation pattern of a putative second terpene synthase divalent metal binding motif in plants

2008

  1. D. Morrone, Xu, M., D Fulton, B., Determan, M. K., and Peters, R. J., “Increasing complexity of a diterpene synthase reaction with a single residue switch”, Journal of the American Chemical Society, vol. 130, no. 16, pp. 5400-5401, 2008. 
    1. Google Scholar: Increasing complexity of a diterpene synthase reaction with a single residue switch

2007

  1. A. Roy, Roberts, F. G., P Wilderman, R., Zhou, K., Peters, R. J., and Coates, R. M., “16-Aza-ent-beyerane and 16-Aza-ent-trachylobane: potent mechanism-based inhibitors of recombinant ent-kaurene synthase from Arabidopsis thaliana”, Journal of the American Chemical Society, vol. 129, no. 41, pp. 12453-12460, 2007.
    1. Google Scholar: 16-Aza-ent-beyerane and 16-Aza-ent-trachylobane:  Potent Mechanism-Based Inhibitors of Recombinant ent-Kaurene Synthase from Arabidopsis thaliana
  2. M. Xu, P Wilderman, R., and Peters, R. J., “Following evolution's lead to a single residue switch for diterpene synthase product outcome”, Proceedings of the National Academy of Sciences, vol. 104, no. 18, pp. 7397-7401, 2007. 
    1. Google Scholar: Following evolution's lead to a single residue switch for diterpene synthase product outcome
  3. M. Xu, P Wilderman, R., Morrone, D., Xu, J., Roy, A., Margis-Pinheiro, M., Upadhyaya, N. M., Coates, R. M., and Peters, R. J., “Functional characterization of the rice kaurene synthase-like gene family”, Phytochemistry, vol. 68, no. 3, pp. 312-326, 2007. 
    1. Google Scholar: Functional characterization of the rice kaurene synthase-like gene family
  4. A. Cyr, P Wilderman, R., Determan, M., and Peters, R. J., “A modular approach for facile biosynthesis of labdane-related diterpenes”, Journal of the American Chemical Society, vol. 129, no. 21, pp. 6684-6685, 2007.
    1. Google Scholar: A modular approach for facile biosynthesis of labdane-related diterpenes
  5. S. Prisic, Xu, J., Coates, R. M., and Peters, R. J., “Probing the role of the DXDD motif in class II diterpene cyclases”, ChemBioChem, vol. 8, no. 8, pp. 869-874, 2007. 
    1. Google Scholar: Probing the role of the DXDD motif in class II diterpene cyclases
  6. R. P Wilderman and Peters, R. J., “A single residue switch converts abietadiene synthase into a pimaradiene specific cyclase”, Journal of the American Chemical Society, vol. 129, no. 51, pp. 15736-15737, 2007.
    1. Google Scholar: A single residue switch converts abietadiene synthase into a pimaradiene specific cyclase
  7. S. Prisic and Peters, R. J., “Synergistic substrate inhibition of ent-copalyl diphosphate synthase: a potential feed-forward inhibition mechanism limiting gibberellin metabolism”, Plant physiology, vol. 144, no. 1, pp. 445-454, 2007. 
    1. Google Scholar: Synergistic Substrate Inhibition of ent-Copalyl Diphosphate Synthase: A Potential Feed-Forward Inhibition Mechanism Limiting Gibberellin Metabolism

2006

  1. R. J. Peters, “Uncovering the complex metabolic network underlying diterpenoid phytoalexin biosynthesis in rice and other cereal crop plants”, Phytochemistry, vol. 67, no. 21, pp. 2307-2317, 2006. 
    1. Google Scholar: Uncovering the complex metabolic network underlying diterpenoid phytoalexin biosynthesis in rice and other cereal crop plants
  2. D. Morrone, Jin, Y., Xu, M., Choi, S. - Y., Coates, R. M., and Peters, R. J., “An unexpected diterpene cyclase from rice: functional identification of a stemodene synthase”, Archives of biochemistry and biophysics, vol. 448, no. 1, pp. 133-140, 2006.
    1. Google Scholar: An unexpected diterpene cyclase from rice: functional identification of a stemodene synthase

2005

  1. L. J. Harris, Saparno, A., Johnston, A., Prisic, S., Xu, M., Allard, S., Kathiresan, A., Ouellet, T., and Peters, R. J., “The maize An2 gene is induced by Fusarium attack and encodes an ent-copalyl diphosphate synthase”, Plant molecular biology, vol. 59, no. 6, pp. 881-894, 2005. 
    1. Google Scholar: The Maize An2 Gene is Induced by Fusarium Attack and Encodes an ent-Copalyl Diphosphate Synthase

2004

  1. M. Xu, Hillwig, M. L., Prisic, S., Coates, R. M., and Peters, R. J., “Functional identification of rice syn‐copalyl diphosphate synthase and its role in initiating biosynthesis of diterpenoid phytoalexin/allelopathic natural products”, The Plant Journal, vol. 39, no. 3, pp. 309-318, 2004. 
    1. Google Scholar: Functional identification of rice syn‐copalyl diphosphate synthase and its role in initiating biosynthesis of diterpenoid phytoalexin/allelopathic natural products
  2. R. P Wilderman, Xu, M., Jin, Y., Coates, R. M., and Peters, R. J., “Identification of syn-pimara-7,15-diene synthase reveals functional clustering of terpene synthases involved in rice phytoalexin/allelochemical biosynthesis”, Plant physiology, vol. 135, no. 4, pp. 2098-2105, 2004. 
    1. Google Scholar: Identification of syn-pimara-7,15-diene synthase reveals functional clustering of terpene synthases involved in rice phytoalexin/allelochemical biosynthesis
  3. R. J. Peters and Croteau, R. B., “Metabolic engineering of plant secondary metabolism”, Handbook of plant biotechnology, 2004. 
    1. Google Scholar: Metabolic engineering of plant secondary metabolism
  4. S. Prisic, Xu, M., P Wilderman, R., and Peters, R. J., “Rice contains two disparate ent-copalyl diphosphate synthases with distinct metabolic functions”, Plant physiology, vol. 136, no. 4, pp. 4228-4236, 2004. 
    1. Google Scholar: Rice Contains Two Disparate ent-Copalyl Diphosphate Synthases with Distinct Metabolic Functions

2003

  1. R. J. Peters and Croteau, R. B., “Alternative termination chemistries utilized by monoterpene cyclases: chimeric analysis of bornyl diphosphate, 1,8-cineole, and sabinene synthases”, Archives of biochemistry and biophysics, vol. 417, no. 2, pp. 203-211, 2003.
    1. Google Scholar: Alternative termination chemistries utilized by monoterpene cyclases: chimeric analysis of bornyl diphosphate, 1,8-cineole, and sabinene synthases
  2. R. J. Peters, Carter, O. A., Zhang, Y., Matthews, B. W., and Croteau, R. B., “Bifunctional abietadiene synthase: mutual structural dependence of the active sites for protonation-initiated and ionization-initiated cyclizations”, Biochemistry, vol. 42, no. 9, pp. 2700-2707, 2003.
    1. Google Scholar: Bifunctional abietadiene synthase: mutual structural dependence of the active sites for protonation-initiated and ionization-initiated cyclizations
  3. O. A. Carter, Peters, R. J., and Croteau, R., “Monoterpene biosynthesis pathway construction in Escherichia coli”, Phytochemistry, vol. 64, no. 2, pp. 425-433, 2003. 
    1. Google Scholar: Monoterpene biosynthesis pathway construction in Escherichia coli

2002

  1. R. J. Peters and Croteau, R. B., “Abietadiene synthase catalysis: conserved residues involved in protonation-initiated cyclization of geranylgeranyl diphosphate to (+)-copalyl diphosphate”, Biochemistry, vol. 41, no. 6, pp. 1836-1842, 2002. 
    1. Google Scholar: Abietadiene synthase catalysis: conserved residues involved in protonation-initiated cyclization of geranylgeranyl diphosphate to (+)-copalyl diphosphate
  2. R. J. Peters and Croteau, R. B., “Abietadiene synthase catalysis: Mutational analysis of a prenyl diphosphate ionization-initiated cyclization and rearrangement”, Proceedings of the National Academy of Sciences, vol. 99, no. 2, pp. 580-584, 2002.
    1. Google Scholar: Abietadiene synthase catalysis: mutational analysis of a prenyl diphosphate ionization-initiated cyclization and rearrangement
  3. M. M. Ravn, Peters, R. J., Coates, R. M., and Croteau, R., “Mechanism of abietadiene synthase catalysis: stereochemistry and stabilization of the cryptic pimarenyl carbocation intermediates”, Journal of the American Chemical Society, vol. 124, no. 24, pp. 6998-7006, 2002. 
    1. Google Scholar: Mechanism of abietadiene synthase catalysis: stereochemistry and stabilization of the cryptic pimarenyl carbocation intermediates

2001

  1. R. J. Peters, Ravn, M. M., Coates, R. M., and Croteau, R. B., “Bifunctional abietadiene synthase: free diffusive transfer of the (+)-copalyl diphosphate intermediate between two distinct active sites”, Journal of the American Chemical Society, vol. 123, no. 37, pp. 8974-8978, 2001. 
    1. Google Scholar: Bifunctional abietadiene synthase: free diffusive transfer of the (+)-copalyl diphosphate intermediate between two distinct active sites
  2. M. Tonelli, Peters, R. J., James, T. L., and Agard, D. A., “The solution structure of the viral binding domain of Tva, the cellular receptor for subgroup A avian leukosis and sarcoma virus”, FEBS letters, vol. 509, no. 2, pp. 161-168, 2001. 
    1. Google Scholar: The solution structure of the viral binding domain of Tva, the cellular receptor for subgroup A avian leukosis and sarcoma virus

2000

  1. R. J. Peters, Flory, J. E., Jetter, R., Ravn, M. M., Lee, H. - J., Coates, R. M., and Croteau, R. B., “Abietadiene synthase from grand fir (Abies grandis): characterization and mechanism of action of the “pseudomature” recombinant enzyme”, Biochemistry, vol. 39, no. 50, pp. 15592-15602, 2000. 
    1. Google Scholar: Abietadiene synthase from grand fir (Abies grandis): characterization and mechanism of action of the “pseudomature” recombinant enzyme
  2. M. M. Ravn, Coates, R. M., Flory, J. E., Peters, R. J., and Croteau, R., “Stereochemistry of the cyclization-rearrangement of (+)-copalyl diphosphate to (-)-abietadiene catalyzed by recombinant abietadiene synthase from Abies grandis”, Organic letters, vol. 2, no. 5, pp. 573-576, 2000. 
    1. Google Scholar: Stereochemistry of the cyclization-rearrangement of (+)-copalyl diphosphate to (−)-abietadiene catalyzed by recombinant abietadiene synthase from Abies grandis

1999

  1. E. D Anderson, Peters, R. J., Wilk, B., and Agard, D. A., “α-Lytic protease precursor: Characterization of a structured folding intermediate”, Biochemistry, vol. 38, no. 15, pp. 4728-4735, 1999.
    1. Google Scholar: α-lytic protease precursor: characterization of a structured folding intermediate

1998

  1. R. J. Peters, Shiau, A. K., Sohl, J. L., D Anderson, E., Tang, G., Silen, J. L., and Agard, D. A., “Pro region C-terminus: protease active site interactions are critical in catalyzing the folding of α-lytic protease”, Biochemistry, vol. 37, no. 35, pp. 12058-12067, 1998. 
    1. Google Scholar: Pro region C-terminus: protease active site interactions are critical in catalyzing the folding of α-lytic protease

1997

  1. L. D. Hernandez, Peters, R. J., Delos, S. E., Young, J. A. T., Agard, D. A., and White, J. M., “Activation of a retroviral membrane fusion protein: soluble receptor-induced liposome binding of the ALSV envelope glycoprotein”, The Journal of cell biology, vol. 139, no. 6, pp. 1455-1464, 1997.
    1. Google Scholar: Activation of a retroviral membrane fusion protein: soluble receptor-induced liposome binding of the ALSV envelope glycoprotein

1995

  1. K. Zingler, Bélanger, Ca, Peters, R., Agard, E., and Young, J. A., “Identification and characterization of the viral interaction determinant of the subgroup A avian leukosis virus receptor.”, Journal of virology, vol. 69, no. 7, pp. 4261-4266, 1995. 
    1. Google Scholar: Identification and characterization of the viral interaction determinant of the subgroup A avian leukosis virus receptor