Publication

Paper can be downloaded from ISU Digital Repository: https://works.bepress.com/hua-bai/
Google Scholar: https://scholar.google.com/citations?hl=en&user=O_5UaCsAAAAJ

( Correspondence author marked with asterisk *) ( Bai lab members in bold, # equal contribution).


Selected Publications:

Acetyl-CoA-mediated autoacetylation of fatty acid synthase as a metabolic switch of de novo lipogenesis in Drosophila
Miao T, Kim J, Kang P, Fujiwara H, Hsu FF, Bai H*.
Proc Natl Acad Sci U S A. 2022 Dec 6;119(49):e2212220119.

Peroxisomal Stress Response and Inter-Organelle Communication in Cellular Homeostasis and Aging
Kim J*, Bai H*. 
Antioxidants (Basel). 2022 Jan 19;11(2):192. 

Impaired peroxisomal import in Drosophila oenocytes causes cardiac dysfunction by inducing upd3 as a peroxikine
Huang K, Miao T, Chang K, Kim J, Kang P, Jiang Q, Simmonds AJ, Di Cara F, and Bai H*.
Nat Commun. 2020 Jun 10;11(1):2943. 

TGFB-INHB/activin signaling regulates age-dependent autophagy and cardiac health through inhibition of MTORC2 
Chang K#, Kang P#, Liu Y, Huang K, Miao T, Sagona AP, Nezis IP, Bodmer R, Ocorr K, Bai H*.
Autophagy. 2020 Oct;16(10):1807-1822. 

RiboTag translatomic profiling of Drosophila oenocytes under aging and induced oxidative stress.
Huang K*, Chen W, Zhu F, Li P, Kapahi P, Bai H*. 
BMC Genomics. 2019 Jan 16;20(1):50. 


2022

Acetyl-CoA-mediated autoacetylation of fatty acid synthase as a metabolic switch of de novo lipogenesis in Drosophila
Miao T, Kim J, Kang P, Fujiwara H, Hsu FF, Bai H*.
Proc Natl Acad Sci U S A. 2022 Dec 6;119(49):e2212220119.     (Previously published on bioRxiv)

mTORC2 protects the heart from high-fat diet-induced cardiomyopathy through mitochondrial fission in Drosophila. 
Liu P#, Chang K#, Requejo G, Bai H*.
Frontiers Cell and Developmental Biology     (Previously published on bioRxiv)

Peroxisomal Stress Response and Inter-Organelle Communication in Cellular Homeostasis and Aging
Kim J*, Bai H*. 
Antioxidants (Basel). 2022 Jan 19;11(2):192. 

Lamp1 mediates lipid transport, but is dispensable for autophagy in Drosophila.
Chaudrhy N, Sica M, Surabhi S, Hernandez DS, Mesquita A, Selimovic A, Riaz A, Bai H, Macintosh GC*, Jenny A*
Autophagy

microRNA-252 and FoxO repress inflammaging by a dual inhibitory mechanism on Dawdle mediated TGF-β pathway in Drosophila.
Wu X, Zhao J, Wang X, Niu K, Wang H, Wang H, Miao T, Yang Y, Ma H, Zhang Y, Pan L, Liu R, Bai H, Liu N*.
Genetics

2021

The Second Annual Symposium of the Midwest Aging Consortium: The Future of Aging Research in the Midwestern United States
Green CL, Englund DA, Das S, Herrerias MM, Yousefzadeh MJ, Grant RA, Clark J, Pak HH, Liu P, Bai H, Prahlad V, Lamming DW, Chusyd DE*. 
J Gerontol A Biol Sci Med Sci
 
Loxl2 is a mediator of cardiac aging in Drosophila melanogaster; genetically examining the role of aging clock genes
Bouska MJ*, Bai H*.
G3: Genes, Genomes, Genetics
 
Metabolism in the Midwest: research from the Midwest Aging Consortium at the 49th Annual Meeting of the American Aging Association
Murphy ME, Narasimhan A, Adrian A, Kumar A, Green CL, Soto-Palma C, Henpita C, Camell C, Morrow CS, Yeh CY, Richardson CE, Hill CM, Moore DL, Lamming DW, McGregor ER, Simmons HA, Pak HH, Bai H, Denu JM, Clark J, Simcox J, Chittimalli K, Dahlquist K, Lee KA, Calubag M, Bouska M, Yousefzadeh MJ, Sonsalla M, Babygirija R, Yuan R, Tsuji T, Rhoads T, Menon V, Jarajapu YP, Zhu Y*.
Geroscience.

Long non-coding RNA regulation of spermatogenesis and endosomal processes via the spectrin cytoskeleton in Drosophila
Bouska M*, Bai H*.
G3: Genes, Genomes, Genetics     (Previously published on bioRxiv)

FOXO regulates neuromuscular junction homeostasis during Drosophila aging
Birnbaum A*, Sodders M, Bouska M, Chang K, Kang P, McNeill E, Bai H*.
Frontiers in Aging Neuroscience    (Previously published on bioRxiv)

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)
Klionsky DJ, ..., Bai H, et al.
Autophagy

2020

Peroxisome import stress impairs ribosome biogenesis and induces endoplasmic reticulum genes
Huang K#, Kim J#, Vo P, Miao T, Bai H*.
bioRxiv.

Liver hepatokines and peroxisomes as therapeutic targets for cardiovascular diseases
Huang K*, Bai H*.
Future Cardiology

Impaired peroxisomal import in Drosophila oenocytes causes cardiac dysfunction by inducing upd3 as a peroxikine
Huang K, Miao T, Chang K, Kim J, Kang P, Jiang Q, Simmonds AJ, Di Cara F, and Bai H*.
Nat Commun. 2020 Jun 10;11(1):2943.    (Previously published on bioRxiv)

2019

TGFB-INHB/activin signaling regulates age-dependent autophagy and cardiac health through inhibition of MTORC2 
Chang K#, Kang P#, Liu Y, Huang K, Miao T, Sagona AP, Nezis IP, Bodmer R, Ocorr K, Bai H*.
Autophagy. 2020 Oct;16(10):1807-1822.    (Previously published on bioRxiv)

Physiological functions of a methuselah-like G protein coupled receptor in Lymantria dispar Linnaeus.
Cao C, Sun L, Du H, Moural T, Bai H, Liu P, Zhu F*. 
Pesticide Biochemistry and Physiology

Age-dependent changes in transcription factor FOXO targeting in female Drosophila
Birnbaum A, Wu X, Tatar M, Liu N*, Bai H*.
Frontiers in Genetics, Genetics of Aging      (Previously published on bioRxiv)

Organelle Aging: Lessons from Model Organisms.
Bouska M, Huang K, Kang P, Bai H*
Journal of Genetics and Genomics

A determining factor for insect feeding preference in the silkworm, Bombyx mori
Zhang ZJ, Zhang SS, Niu BL, Ji DF, Liu XJ, Li MW, Bai H, Palli SR, Wang CZ, Tan AJ. 
PLoS Biology

RiboTag translatomic profiling of Drosophila oenocytes under aging and induced oxidative stress.
Huang K*, Chen W, Zhu F, Li P, Kapahi P, Bai H*. 
BMC Genomics. 2019 Jan 16;20(1):50. 

2017

Drosophila Kruppel homolog 1 represses lipolysis through interaction with dFOXO.
Kang P, Chang K, Liu Y, Bouska M, Birnbaum A, Karashchuk G, Thakore R, Zheng W, Post S, Brent C, Li S, Tatar M*, Bai H*.
Scientific Reports

The FOXO transcription factor controls insect growth and development by regulating juvenile hormone degradation in the silkworm, Bombyx mori.
Zeng B, Huang Y, Xu J, Shiotsuki T, Bai H, Palli SR, Huang Y, Tan A*.
Journal Biological Chemistry

2016
    
Identification of G protein-coupled receptors required for vitellogenin uptake into the oocytes of the red flour beetle, Tribolium castaneum.
Bai H *, Palli SR*.
Scientific Reports

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).
Klionsky DJ, ..., Bai H, et al.
Autophagy

2015

Drosophila longevity assurance conferred by reduced insulin receptor substrate chico requires 4E-BP.
Bai H, Post S, Kang P, Tatar M*.
PLoS One

Tequila regulates insulin-like signaling and extends life span in Drosophila melanogaster.
Huang CW, Wang HD, Bai H, Wu MS, Yen JH, Tatar M, Fu TF, Wang PY*.
Journal of Gerontology: Biological Sciences

2013

Activin signaling targeted by insulin/dFOXO regulates aging and muscle proteostasis in Drosophila.
Bai H, Kang P, Hernandez AM, Tatar M*.
PLoS Genetics

Juvenile hormone regulation of Drosophila aging.
Yamamoto R, Bai H, Dolezal AG, Amdam G, Tatar M*.
BMC Biology

2012

Drosophila insulin-like peptide-6 (dilp6) expression from fat body extends lifespan and represses secretion of Drosophila insulin-like peptide-2 from the brain.
Bai H, Kang P, Tatar M*.
Aging Cell

Minibrain/Dyrk1a regulates food intake through the Sir2-FOXO-sNPF/NPY pathway in Drosophila and mammals.
Hong S-H, Lee K-H, Kwak S-H, Kim A-K, Bai H, Jung M-S, Kwon O-Y, Song W-J, Tatar M, Yu K*.
PLoS Genetics    

2011

Juvenile hormone regulates vitellogenin gene expression through insulin-like peptide signaling pathway in the red flour beetle, Tribolium castaneum.
Sheng Z, Xu J, Bai H, Zhu F, Palli SR*.
Journal of Biological Chemistry 

Large-scale RNAi screen of G protein-coupled receptors involved in larval growth, molting and metamorphosis in the red flour beetle.
Bai H, Zhu F, Shah K, Palli SR*.
BMC Genomics    

2010

Mode of action of methoprene in affecting female reproduction in the African malaria mosquito, Anopheles gambiae.
Bai H, Gelman D. B, Palli SR*.
Pest Management Science

Functional characterization of bursicon receptor and genome-wide analysis for identification of genes affected by bursicon receptor RNAi. 
Bai H, Palli SR*.
Developmental Biology 

A brain-specific cytochrome P450 responsible for the majority of deltamethrin resistance in the QTC279 strain of Tribolium castaneum.
Zhu F, Parthasarathy R, Bai H, Woitheb K, Kaussmannb M, Nauenb R, Harrison DA, Palli SR*.
The Proceedings of the National Academy of Sciences of the U.S.A. (PNAS)  

Juvenile hormone regulation of vitellogenin synthesis in the red flour beetle, Tribolium castaneum.
Parthasarathy R, Sun Z, Bai H, Palli SR*.
Insect Biochemistry and Molecular Biology

2009

The mandibular organ in crustacean and a radiochemical assay for methyl farnesoate.
Lu J, Chang G, Wu X, Bai H, Zhao W, Cheng Y*.
Fisheries Science, 28(2):113-116.     

2008

Transcription factor broad suppresses precocious development of adult structures during larval-pupal metamorphosis in the red flour beetle, Tribolium castaneum.
Parthasarathy R, Tan A, Bai H, Palli SR*.
Mechanisms of Development

2007

Identification and characterization of juvenile hormone esterase gene from the yellow fever mosquito, Aedes aegypti.
Bai H, Parthasarathy R, Palli SR*.
Insect Biochemistry and Molecular Biology  

2006

Mechanisms of midgut remodeling: Juvenile hormone analog methoprene blocks midgut metamorphosis by modulating ecdysone action.
Wu Y, Parthasarathy R, Bai H, Palli SR*.
Mechanisms of Development   

In vitro regulation of hormone biosynthesis of the mandibular organ in crayfish, Procambarus clarkia.
Lu J, Bai H, Cheng Y, Zhao W*.
Journal of Fisheries of China. Vol.13, No.3, 471-474.     

2002

The regulation of methyl farnesoate biosynthesis in Procambarus clarkii. 
Zhao W*, Bai H, Lu J.
Journal of Fisheries of China. Vol.26, Suppl. 1-6.     

Effects of the Chinese herb, Radix polygoni multiflori on MPTP-induced mouse model of Parkinson’s disease. 
Yuan C*, Bai H, Yang F.
Journal of East China Normal University (Natural Science). No.3, 95-98.     

2001

The biosynthesis of methyl farnesoate by the mandibular organ in crayfish, Procambarus clarkii.
Zhao W*, Bai H.
Journal of Fisheries of China. Vol.25, No.3, 193-196.     

1999

Changes in progesterone contents of the ovary and mandibular organ in crayfish during vitellogenesis.
Zhao W*, Bai H, Ma X.
Journal of Shanghai Fisheries University. Vol.8, No.3, 232-236.  

Book chapters     

Bai H, 2012. Genome-Wide RNAi Screen for the Discovery of Gene Function, Novel Therapeutical Targets and Agricultural Applications. In: Functional genomics. Meroni G. and Petrera F. (ed). InTech. DOI: 10.5772/49945     

Bai H, Palli SR. 2012. G protein-coupled receptors as target sites for insecticide discovery. In: Advanced Technologies for Controlling Insect Pests. Ishaaya I, Palli S.R, Horowitz A.R. (ed). Springer Science.     

Palli SR, Bai H, Wigginton J. 2011. Insect genomics and beyond. In: Insect Biochemistry and Molecular Biology. Gilbert L. (ed). Springer Science.     

Garry NH, Hill RJ, Dedos SG, Swevers L, Latrou K, Tan A, Parthasarathy R, Bai H, Zhang Z, Palli SR. 2009. Applications of RNA interference in ecdysone research. In: Ecdysone, structures and functions. G. Smaghhe (ed). Springer Science, 205-227.