
Given the universality of ribosomes and the almost absolute conservation of the RNase T2 family in eukaryotes, we hypothesized that the mechanism of rRNA turnover was also highly conserved in other higher organisms.
All research in the MacIntosh laboratory is multidisciplinary and highly collaborative. Although most of our research uses plant models (mainly Arabidopsis and soybean), we also work on other eukaryote models to answer specific questions. Our research is centered around two big questions: