soybean aphid

soybean aphid
Photo credit: Ted C. MacRae

The MacIntosh Lab

Welcome to the MacIntosh Lab @ Iowa State University. Our lab works on a variety of things, mostly centered around two big questions:


How do eukaryotic cells recycle ribosomes?

We want to know how cells transport ribosomes to the vacuole or lysosome, and the ribonucleases and other enzymes associated with the RNA salvage pathway.


What are the molecular bases of compatible and incompatible interactions between plants and insects?

We try to understand what are the mechanisms that plants (mainly soybean) use as defense against aphids, and the strategies used by aphids to avoid these defenses

Latest Publication

Isoflavone profile

Transcriptional and chemical changes in soybean leaves in response to long-term Aphid colonization

Hohenstein et al (2019)

Frontiers in Plant Science 10, 310

News

  • The lab welcomes Ludvic Mejia (Biology senior), who has been accepted in the IINSPIRE-LSAMP program for the summer and will work on plant-insect interactions
  • Sarah Grambo (Biochem senior) received the Dean’s High Impact Award from the College of Liberal Arts and Sciences, to conduct summer research in the lab. She will continue with the characterization of cuticle changes in soybean leaves in response to aphid feeding
  • Brandon Buscher (Biochem junior) received the Dean’s High Impact Award from the College of Liberal Arts and Sciences, to conduct summer research in the lab. He will continue with the characterization vacuolar phosphatases involved in the RNA salvage pathway