Highlighted SCID Works (newest to oldest)
Singer, A.J. et al. Survival of Human Cadaver Skin on SCID Pigs: Proof of Concept. Wound Repair Regen. 2020. 27 (4): 426-430
Boettcher A.N. and Li, Y et al. Novel Engraftment and T cell Differentiation of Human Hematopoietic Cells in ART-/- IL2RG-/Y SCID Pigs. Front. Immunol. 2020. 11: 100
Annamalai T. et al. Infectivity of GII.4 human norovirus does not differ between T-B-NK+ severe combine immunodeficiency (SCID) and non-SCID gnotobiotic pigs, implicating the role of NK cells in mediation of human norovirus infection. Virus Res. 2019. 267: 21-25
Boettcher A.N. et al. Human Ovarian Cancer Tumor Formation in Severe Combined Immunodeficient Pigs. Front Oncol. 2019. 9: 9
Boettcher, A.N. et al. Porcine SIRPA Binds to Human CD47 to Inhibit Phagocytosis: Implications for Human Hematopoietic Stem Cell Transplantation into Severe Combined Immunodeficient Pigs. Xenotransplantation. 2019. 26 (2): e12466
Powell, E.J. et al. Creating Effective Biocontainment Facilities and Maintenance Protocols for Raising Specific Pathogen-free, Severe Combined Immunodeficient (SCID) Pigs. Lab Anim. 2018. 52 (4): 402-412
Powell, E.J. et al. NK cells are Intrinsically Functional in Pigs with Severe Combined Immunodeficiency (SCID) caused by Spontaneous Mutations in the Artemis Gene. Vet Immunol Immunopathol. 2016. 175: 1-6
Waide, E.H. et al. Not All SCID Pigs Are Created Equally: Two Independent Mutations in the Artemis Gene Cause SCID in Pigs. J Immunol. 2015. 195 (7): 3171-3179
SCID Pig Review Articles
Boettcher A.N. et al. Development of Severe Combined Immunodeficient (SCID) Pig Models for Translational Cancer Modeling: Future Insights on How Humanized SCID Pigs Can Improve Preclinical Cancer Research. Front Oncol. 2018. 8: 559
Powell E.J. et al. SCID Pigs: an Emerging Large Animal NK Model. J Rare Dis Res Treat. 2017. 2(3): 1-6
Highlighted FAANG Research, Review Articles, and White Papers
Herrera-Uribe, J. et al. Changes in H3K27ac at Gene Regulatory Regions in Porcine Alveolar Macrophages Following LPS or PolyIC Exposure. Front. Genetics. 2020. 11: 817
Herrera-Uribe, J and Wiarda, JE et al. Reference transcriptomes of porcine peripheral immune cells created through bulk and 1single-cell RNA sequencing. Submitted to BioRxiv April 4, 2021.
Clark E. et al. From FAANG to Fork: Application of Highly Annotated Genomes to Improve Farmed Animal Production. Genome Biol. 2020. 21: 285
Giuffra E. et al. Functional Annotation of ANimal Genomes (FAANG): current achievements and roadmap. Annual Review of Animal Biosciences. 7: 65-88.
Tuggle CK. et al. GO-FAANG: a Gathering On Functional Annotation of ANimal Genomes. Animal Genetics. 47: 528-533.
The FAANG Consortium (49 authors, CK Tuggle as co-corresponding author). Coordinated international action to accelerate genome to phenome with FAANG, the Functional Annotation of Animal Genomes project. Genome Biology. 2015. 16:57