DS = (biomedical) data science / applied statistics
EPI = mathematical epidemiology / infectious disease modeling
GRN = gene regulatory (Boolean) networks
* = lead/shared lead and/or corresponding author


  • [GRN & DS*] C Kadelka, T Butrie, E Hilton, J Kinseth, A Schmidt, H Serdarevic. "A meta-analysis of Boolean network models reveals design principles of gene regulatory networks" Science Advances [see also project website; ScienceDaily]
  • [EPI*] G Gonzalez-Parra, MS Mahmud, C Kadelka. "Learning from the COVID-19 pandemic: a systematic review of mathematical vaccine prioritization models" medRxiv (preprint)
  • [GRN*] C Kadelka, D Murrugarra. "Canalization reduces the nonlinearity of regulation in biological networks" Arxiv (preprint)
  • [GRN*] M Wheeler, C Kadelka, A Veliz-Cuba, D Murrugarra, R Laubenbacher. "Modular construction of Boolean networks" Arxiv (preprint)
  • [GRN] D Murrugarra, A Veliz-Cuba, E Dimitrova, C Kadelka, M Wheeler, R Laubenbacher. "Modular control of biological networks" Arxiv (preprint)



  • [DS*] X Jia, A Phan, C Kadelka. "Concise functional enrichment of ranked gene lists" bioRxiv (preprint)
  • [EPI*] C Kadelka. "Projecting social contact matrices to populations stratified by binary attributes with known homophily" Mathematical Biosciences and Engineering
  • [GRN*] C Kadelka, B Keilty, R Laubenbacher. "Collectively canalizing Boolean functions" Advances in Applied Mathematics (free pdf: Arxiv)
  • [GRN*] C Kadelka, M Wheeler, A Veliz-Cuba, D Murrugarra, R Laubenbacher, "Modularity of biological systems: a link between structure and function" Journal of the Royal Society Interface 
  • [GRN] K Chandrasekhar, C Kadelka, R Laubenbacher, D Murrugarra. "Stability of linear Boolean networks" Physica D: Nonlinear Phenomena
  • [OTHER] C Renard, H Brick, J-F Maingonnat, C Kadelka, N Delchier. "­­­­Relative role of leaching and chemical degradation in the loss of water-soluble vitamins C and B9 from frozen vegetables cooked in water" LWT - Food Science and Technology
  • [OTHER] K Borchardt, C Kadelka, L Schulte, A Toth. "An ecological networks approach reveals restored native vegetation benefits wild bees in agroecosystems" Biological Conservation



  • [EPI*] C Kadelka, R Islam, A McCombs, J Alston, N Morton. "Ethnic homophily affects vaccine prioritization strategies" Journal of Theoretical Biology (free pdf: medRxiv) [see also ISU News]
  • [GRN] E Dimitrova, B Stigler, C Kadelka, D Murrugarra. "Revealing the canalizing structure of Boolean functions: Algorithms and applications" Automatica



  • [DS] N Friedrich, E Stiegeler, M Glögl, T Lemmin, S Hansen, C Kadelka, Y Wu, P Ernst, L Maliqi, C Foulkes, M Morin, M Eroglu, T Liechti, B Ivan, T Reinberg, J Schaefer, U Karakus, S Ursprung, A Mann, P Rusert, R Kouyos, J Robinson, H Gunthard, A Plückthun, and A Trkola. "Distinct conformations of the HIV-1 V3 loop crown are targetable for broad neutralization" Nature Communications
  • [EPI*] R Islam, T Oraby, A McCombs, MM Chowdhury, M Al-Mamun, MG Tyshenko, C Kadelka. "Evaluation of the United States COVID-19 vaccine allocation strategy" PLOS One [see also The Conversation, Futurity, The AtlanticHealthline]
  • [EPI*] C Kadelka, A McCombs. "Effect of clustering and correlation of belief systems on COVID-19 and general infectious disease outbreaks" PLOS One
  • [EPI] N Bachmann, K Kusejko, H Nguyen, SE Chaudron, C Kadelka, T Turk, J Boni, M Perreau, T Klimkait, S Yerly, M Battegay, A Rauch, A Ramette, P Vernazza, E Bernasconi, M Cavassini, HF Gunthard, RD Kouyos. “Phylogenetic cluster analysis identifies virological and behavioral drivers of HIV transmission in MSM.” Clinical Infectious Diseases





  • [DS] T Liechti, C Kadelka, DL Braun, H Kuster, J Boni, M Robbiani, HF Gunthard, A Trkola. “Widespread B cell perturbations in HIV-1 infection afflict naive and marginal zone B cells.”  Journal of Experimental Medicine
  • [DS] N Bachmann, A von Braun, N Labhardt, C Kadelka, HF Gunthard, C Sekaggya- Wiltshire, B Castelnuovo, A Kambugu, I Ringera, J Boni, S Yerly, M Perreau, T Klimkait, RD Kouyos, J Fehr, the Swiss HIV Cohort Study. “The importance of routine viral load monitoring: Higher levels of resistance at antiretroviral therapy failure in Uganda and Lesotho compared to Switzerland.” Journal of Antimicrobial Chemotherapy 
  • [OTHER] I Abela, C Kadelka, A Trkola. “Correlates of broadly neutralizing antibody development.” Current Opinion in HIV and AIDS


  • [DS*] C Kadelka, T Liechti, H Ebner, M Schanz, P Rusert, N Friedrich, E Stiegeler, DL Braun, M Huber, AU Scherrer, J Weber, T Uhr, H Kuster, B Misselwitz, M Cavassini, E Bernasoni, M Hoffmann, A Calmy, M Battegay, A Rauch, S Yerly, V Aubert, T Klimkait, J Boni, RD Kouyos, HF Gunthard, A Trkola. “Distinct, IgG1 driven antibody response landscapes demarcate individuals with broadly HIV-1 neutralizing activity.” Journal of Experimental Medicine
  • [DS*] T Liechti, C Kadelka, H Ebner, N Friedrich, RD Kouyos, HF Gunthard, A Trkola. “Development of a high-throughput bead based assay system to measure HIV- 1 specific immune signatures in clinical samples.” Journal of Immunological Methods
  • [DS] L Reh, C Magnus, C Kadelka, T Uhr, J Weber, L Morris, PL Moore, A Trkola. “Viral escape from the CAP256-VRC26 bnAb lineage is associated with slower entry kinetics and increased cell-cell transmission capacity.” PLOS Pathogens
  • [DS & EPI*] R Kouyos, P Rusert, C Kadelka, M Huber, A Marzel, H Ebner, M Schanz, T Liechti, N Friedrich, DL Braun, AU Scherrer, J Weber, T Uhr, NS Baumann, C Leemann, H Kuster, JP Chave, M Cavassini, E Bernasoni, M Hoffmann, A Calmy, M Battegay, A Rauch, S Yerly, V Aubert, T Klimkait, J Boni, KJ Metzner, HF Gunthard, A Trkola. “Tracing HIV-1 strains that imprint broadly neutralizing responses.” Nature [see also Newsweek]
  • [EPI] K Kusejko, C Kadelka, A Marzel, M Battegay, E Bernasoni, A Calmy, M Cavassini, M Hoffmann, J Boni, S Yerly, T Klimkait, M Perreau, A Rauch, HF Gunthard, RD Kouyos, the Swiss HIV Cohort Study. “Inferring age-assortative mixing patterns by applying phylogenetic methods on the HIV transmission tree of the Swiss HIV Cohort Study.” Virus Evolution



  • [GRN*] C Kadelka, J Kuipers, R Laubenbacher. “The influence of canalization on the robustness of Boolean networks.” Physica D: Nonlinear Phenomena
  • [GRN*] C Kadelka, Y Li, J Kuipers, JO Adeyeye, R Laubenbacher. “Multistate nested canalizing functions and their networks.” Theoretical Computer Science
  • [EPI] T Turk, N Bachmann, C Kadelka, J Boni, S Yerly, V Aubert, T Klimkait, M Battegay, E Bernasoni, A Calmy, M Cavassini, H Furrer, M Hoffmann, HF Gunthard, RD Kouyos. “Assessing the danger of self-sustained HIV epidemics in heterosexuals by population based phylogenetic cluster analysis.” eLife
  • [DS] N Bachmann, T Turk, C Kadelka, A Marzel, M Shilaih, J Boni, V Aubert, T Klimkait, GE Leventhal, HF Gunthard, RD Kouyos. “Parent-offspring regression to estimate the heritability of an HIV-1 trait in a realistic setup.” Retrovirology
  • [DS] D Beauparlant, P Rusert, C Magnus, C Kadelka, J Weber, T Uhr, O Zagordi, C Oberle, MJ Duenas-Decamp, P Clapham, KJ Metzner, HF Gunthard, A Trkola. “Delineating CD4 dependency of HIV-1: Adaptation to infect low level CD4 expressing target cells widens cellular tropism but severely impacts on envelope functionality.” PLOS Pathogens


  • [DS] P Rusert, RD Kouyos, C Kadelka, H Ebner, M Schanz, M Huber, DL Braun, AU Scherrer, C Magnus, J Weber, T Uhr, V Cippa, CW Thorball, H Kuster, M Cavassini, E Bernasoni, M Hoffmann, A Calmy, M Battegay, A Rauch, S Yerly, V Aubert, T Klimkait, J Boni, J Fellay, R Regoes, HF Gunthard, A Trkola. “Determinants of HIV-1 broadly neutralizing antibody induction.” Nature Medicine


  • [GRN*] C Kadelka, D Murrugarra, R Laubenbacher. “Stabilizing gene regulatory networks through feedforward loops.” Chaos