Manoj Kumar

Manoj Kumar

Position
  • Postdoc Research Associate
Professional Bio
Dr. Manoj Kumar is a postdoctoral research associate at Iowa State University with over a decade of experience in immunology, molecular diagnostics, and pathogen research. His work focuses on developing and characterizing 3D Matrigel-based and Air Liquid interface (ALI) cultures of porcine respiratory cells, and applying advanced microscopy and histological tools to investigate respiratory pathogens. He is also involved in automating high-throughput PCR workflows to detect E. coli and its toxins using 384-well qPCR platforms.

Dr. Kumar’s previous work in Singapore and India included immunological characterization of dengue virus, development of recombinant subunit vaccines against Bacillus anthracis, and lateral flow and ELISA-based assays for mycotoxins. He has contributed to diagnostic and vaccine development projects under high-containment (BSL-3) lab settings and has published in several peer-reviewed journals. His research integrates classical microbiology, vaccine immunology, and molecular diagnostic technologies to address emerging public and veterinary health challenges.

Contact

Patterson Hall
1800 Christensen Dr
Ames
,
IA
50011-1134
Social Media and Websites

Education

  • BSc in Zoology, Jiwaji University, India
  • MSc in Biotechnology, Jiwaji University, India
  • PhD in Biological Science, Bharathiar University, India

Work Experiences 

TimelinePositions
2011Project Trainee, Defence Research and Development Establishment, DRDO, India
2013-2014Research Scholar, Mazumdar Shaw Medical Center, India.
2015-2020Research Fellow, Defence Research and Development Establishment, DRDO, India
2020-2023Senior Project Associate, CSIR-Indian Institute of Toxicology, India
2023-2024Post-doctoral, DUKE-NUS Medical School, National University of Singapore, Singapore
2024-presentPostdoc Research Associate, College of Veterinary Medicine, Iowa State University

Research Interests

  • Development and characterization of 3D and air-liquid interface (ALI) cultures of porcine respiratory cells for functional and molecular profiling.
  • Investigation of influenza virus interactions with porcine respiratory organoids to study host-pathogen dynamics.
  • Application of histological analysis and advanced imaging techniques, including confocal and light sheet microscopy, to analyze organoid responses.
  • Investigation of dengue virus pathogenesis through viral propagation, neutralization assays (PRNT), and immune profiling in mast cell-deficient mice using multicolor flow cytometry.
  • Development and immunological evaluation of recombinant subunit vaccines against Bacillus anthracis, including antigen design, expression, and efficacy assessment in murine models.