Laboratory of Evolutionary and Ecological Genomics
LingSze Lee

Dr. LingSze Lee

Position
  • Postdoc
LingSze was a postdoctoral associate and former PhD student. For her Master's degree she studied human chromosome sequence variation, and her PhD dissertation included cytogenetics studies on the evolution of sex chromosomes and genome organization in turtles. She worked on turtle chromosome evolution during her postdoc at ISU.

LingSze is now a Postdoc / Research Specialist II in the Unit on Chromosome Dynamics, Division of Developmental Biology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, USA National Institutes of Health.

6.  Bista B, González-Rodelas L, Álvarez-González L, Wu ZQ, Montiel EE, Lee LS, Badenhorst DB, Radhakrishnan S, Literman R, Navarro-Dominguez B, Iverson JB, Orozco-Arias S,  González J, Ruiz-Herrera A, Valenzuela N. 2024. De novo genome assemblies of two cryptodiran (hidden-neck) turtles with ZZ/ZW and XX/XY sex chromosomes provide insights into patterns of genome reshuffling and uncover novel 3D genome folding in amniotes. Genome Research. In Press.

5. Montiel EE, Badenhorst D, Lee LS, Valenzuela N. 2022. Evolution and dosage compensation of nucleolar organizing regions (NORs) mediated by mobile elements in turtles with female (ZZ/ZW) but not with male (XX/XY) heterogamety. Journal of Evolutionary Biology. 35:1709–1720.

4. Lee LS, Navarro-Domínguez BM, Wu Z, Montiel EE, Badenhorst D, Bista B, Gessler TB, and Valenzuela N. 2020. Karyotypic evolution of sauropsid vertebrates illuminated by optical and physical mapping of the painted turtle and slider turtle genomes. Genes, 11, 928, doi:10.3390/genes11080928.

3. Lee LS, Montiel EE, and Valenzuela N. 2019. Discovery of putative XX/XY male heterogamety in Emydura subglobosa turtles exposes a novel trajectory of sex chromosome evolution in Emydura. Cytogenetic and Genome Research 158:160–169.

2. Lee LS, EE Montiel, BM Navarro-Domínguez, and N Valenzuela. 2019. Chromosomal rearrangements during turtle evolution altered the synteny of genes involved in vertebrate sex determination Cytogenetic and Genome Research  157:77-88. 

1. Montiel EE, D Badenhorst, LS Lee, R Literman, V Trifonov, and N Valenzuela. 2016. Cytogenetic insights into the evolution of chromosomes and sex determination reveal striking homology of turtle sex chromosomes to amphibian autosomes. Cytogenetic and Genome Research 148:292-304.