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Daleen Badenhorst

Dr. Daleen Badenhorst

  • Former Postdoctoral Associate
Daleen was a postdoctoral fellow. Her PhD work focused on the Rattus complex and its role as a reservoir for human pathogens using a molecular cytogenetic, phylogenomic and gene expression approach.

At the Valenzuela lab she first worked on a phylogenomics project to study the evolution of sex chromosomes and sex-linked genes in turtles. This work was funded by the National Science Foundation (MCB 0815354 to N. Valenzuela and S.V. Edwards).

Daleen then worked on another phylogenomics project to study the repatterning of turtle genomes responsible for the co-evolution of diploid number and sex determination in turtles. This work is funded by another grant from the National Science Foundation (MCB 1244355 to N. Valenzuela).
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9. Montiel EE, Badenhorst D, Lee LS, Valenzuela N. Evolution and dosage compensation of nucleolar organizing regions (NORs) mediated by mobile elements in turtles with female (ZZ/ZW) but not with male (XX/XY) heterogamety. Journal of Evolutionary Biology. 35:1709–1720.

8. Lee LS, Navarro-Domínguez BM, Wu Z, Montiel EE, Badenhorst D, Bista B, Gessler TB, and Valenzuela N. 2020. Karyotypic evolution of sauropsid vertebrates illuminated by optical and physical mapping of the painted turtle and slider turtle genomes. Genes, 11, 928, doi:10.3390/genes11080928.

7. Montiel EE, D Badenhorst, J Tamplin, R Burke, and N Valenzuela. 2017. Discovery of youngest sex chromosomes reveals first case of convergent co-option of ancestral autosomes in turtles. Chromosoma. 126:105–113.

6. Montiel EE, D Badenhorst, LS Lee, R Literman, V Trifonov, and N Valenzuela. 2016. Cytogenetic insights into the evolution of chromosomes and sex determination reveal striking homology of turtle sex chromosomes to amphibian autosomes. Cytogenetic and Genome Research. 148:292-304.

5. Badenhorst D, LD Hillier, R Literman, EE Montiel, S Radhakrishnan, P Minx, DE Janes, WC Warren, SV Edwards, and N Valenzuela. 2015. Physical mapping and refinement of the painted turtle genome (Chrysemys picta) inform amniote genome evolution and challenges turtle-bird chromosomal conservation. Genome Biology and Evolution 7(7):2038–2050.

4. Literman R, Badenhorst D, Valenzuela N. 2014. QPCR-based molecular sexing by copy number variation in rRNA genes and its utility for sex identification in soft-shell turtles. Methods in Ecology and Evolution 5: 872-880.

3. Valenzuela N, D Badenhorst, EE Montiel Jimenez, R. Literman. 2014. Molecular cytogenetic search for cryptic sex chromosomes in painted turtles Chrysemys pictaCytogenetic and Genome Research 144: 39-46.

2. Shaffer HB, P Minx, DE Warren, AM Shedlock, RC Thomson, N Valenzuela,....D. Badenhorst et 40 altri. 2013. The western painted turtle genome, a model for the evolution of extreme physiological adaptations in a slowly evolving lineage. Genome Biology. doi:10.1186/gb-2013-14-3-r28

1. Badenhorst, D., R. Stanyon, T. Engstrom, and N. Valenzuela. 2013. A ZZ/ZW microchromosome system in the spiny softshell turtle, Apalone spinifera reveals an intriguing sex chromosome conservation in Trionychidae. Chromosome Research. 12(2): 137-147.