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Dr. Beatriz Mizoguchi

Dr. Beatriz Mizoguchi

  • Former Graduate Student
I graduated from the Interdepartmenal Genetics and Genomics program in 2020. I was a Science Without Borders/LASPAU fellow from Brazil. I am interested in the phenotypic responses to environmental insult, such as exposure to toxins, and the effect that they have on DNA methylation and gene expression.
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6. Mizoguchi B.A. and Valenzuela N2023. A cautionary tale of sexing by methylation: Hybrid bisulfite-conversion sequencing of immunoprecipitated methylated DNA in Chrysemys picta turtles with temperature-dependent sex determination reveals contrasting patterns of somatic and gonadal methylation. Animals. In press.

5. Mizoguchi1 B, Topping NE, Lavin AM and Valenzuela N. 2022. Cadmium ecotoxic effects on embryonic Dmrt1 and aromatase expression in Chrysemys picta turtles may implicate changes in DNA methylation. Genes. 13, 1318.

4. Mizoguchi B.A. and Valenzuela N. 2020. Alternative splicing and thermosensitive expression of Dmrt1 during urogenital development in the painted turtle, Chrysemys picta. PeerJ 8:e8639.

3. Valenzuela N, R Literman, JL Neuwald, BA Mizoguchi, JB Iverson, JL Riley, and JD Litzgus. 2019. Extreme thermal fluctuations from climate change unexpectedly accelerate demographic collapse of vertebrates with temperature-dependent sex determination. Scientific Reports. DOI: 10.1038/s41598-019-40597-4

2. Radhakrishnan S, Literman R, Mizoguchi B, and Valenzuela N. 2017. MeDIPseq and nCpG analyses illuminate sexually dimorphic methylation of gonadal development genes with high historic methylation in turtle hatchlings with temperature-dependent sex determination. Epigenetics & Chromatin 10: 28. DOI 10.1186/s13072-017-0136-2

1. Mizoguchi BA and N Valenzuela. 2016. Ecotoxicological perspectives of sex determination. Sexual Development 10:45-57. DOI:10.1159/000444770.