Current projects that are underway in the Keating Lab
Investigating ovarian DNA damaging impacts of environmental toxicant exposures such as glyphosate and Perfluorooctanoic acid and additive impact of obesity.
Determining the involvement of ovarian prolactin signaling in subfertility caused by heat stress and obesity using rodent and porcine models.
Determining impacts of gestational exposure to a genotoxicant on maternal and offspring ovarian function.
Evaluating developmental and physiological status effects on ovotoxicity.
Elucidating mechanisms in the ovary that regulate chemical metabolism and whether obesity alters these modes of action.
Investigating impact of genotoxicant exposure on ovarian DNA damage and the ovarian protective response.
Determining adverse outcome pathways due to ovotoxicant exposures.
Examining how the ovary biotransforms chemical exposures (zearalenone, Perfluorooctanoic acid) and if obesity alters ovarian chemical metabolism.